Afshan Anjum, Sadaf Nigar
Obstetrics and Gynaecology, Ziauddin University, Karachi.
J Pak Med Assoc. 2013 Apr;63(4):519-20.
Primary ovarian lymphoma is very rare. Ovarian involvement by non-Hodgkin's lymphoma is usually secondary, occurring as part of a systemic disease. We report a case of primary diffuse large B-cell lymphoma of the ovary manifesting as advanced ovarian cancer. The diagnosis was confirmed on histological and immunohistochemical analysis. The patient was treated with surgery followed by chemotherapy using rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone (R-CHOP) regimen.
原发性卵巢淋巴瘤非常罕见。非霍奇金淋巴瘤累及卵巢通常是继发性的,是全身性疾病的一部分。我们报告一例表现为晚期卵巢癌的原发性卵巢弥漫性大B细胞淋巴瘤病例。经组织学和免疫组化分析确诊。患者接受了手术治疗,随后采用利妥昔单抗、环磷酰胺、阿霉素、长春新碱和泼尼松龙(R-CHOP)方案进行化疗。