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钙波的机械化学耦联。

Calcium waves with mechano-chemical couplings.

机构信息

Institute of Fundamental Technological Research, Polish Academy of Sciences, Pawinskiego 5B, 02-106 Warsaw, Poland.

出版信息

Math Biosci Eng. 2013 Jun;10(3):743-59. doi: 10.3934/mbe.2013.10.743.

Abstract

As follows from experiments, waves of calcium concentration in biological tissues can be easily excited by a local mechanical stimulation. Therefore the complete theory of calcium waves should also take into account coupling between mechanical and chemical processes. In this paper we consider the existence of travelling waves for buffered systems, as in [22], completed, however, by an equation for mechanical equilibrium and respective mechanochemical coupling terms. Thus the considered, coupled system consists of reaction-diffusion equations (for the calcium and buffers concentrations) and equations for the balance of mechanical forces.

摘要

从实验可以看出,生物组织中的钙离子浓度波很容易被局部机械刺激激发。因此,完整的钙离子波理论还应该考虑机械过程和化学过程之间的耦合。在本文中,我们考虑了缓冲系统的行波存在,就像[22]中那样,但完成了机械平衡和相应的机械化学耦合项的方程。因此,所考虑的耦合系统由反应扩散方程(用于钙和缓冲物浓度)和机械力平衡方程组成。

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