Sato Taku, Kishida Yugo, Watanabe Tadashi, Tani Akiko, Tada Yasuhiro, Tamura Takamitsu, Ichikawa Masahiro, Sakuma Jun, Omori Koichi, Saito Kiyoshi
Department of Neurosurgery, Fukushima Medical University.
No Shinkei Geka. 2013 Aug;41(8):693-6.
We evaluated the effectiveness of intraoperative topical application of fluorescein to detect the leakage point of cerebrospinal fluid(CSF)rhinorrhea. Three patients with CSF rhinorrhea were treated with an endoscopic endonasal technique. Ten percent fluorescein was topically used for intraoperative localization of the leak site. A change of the fluorescein color from brown to green due to dilation of CSF were recognized as evidence of CSF rhinorrhea. We repeated the procedure to detect any small defects. All CSF rhinorrheas were successfully repaired by this endoscopic endonasal approach. Topical application of fluorescein is simple and sensitive for identifying intraoperative CSF rhinorrhea.
我们评估了术中局部应用荧光素检测脑脊液鼻漏漏点的有效性。3例脑脊液鼻漏患者采用鼻内镜鼻内技术进行治疗。术中局部使用10%的荧光素对漏口进行定位。由于脑脊液的稀释，荧光素颜色从棕色变为绿色被视为脑脊液鼻漏的证据。我们重复该操作以检测任何小的缺损。所有脑脊液鼻漏均通过这种鼻内镜鼻内入路成功修复。局部应用荧光素在识别术中脑脊液鼻漏方面简单且灵敏。
