灭绝古人类的认知能力：使用基因组证据推翻等级制度。
The cognitive ability of extinct hominins: bringing down the hierarchy using genomic evidences.
机构信息
Departamento de Genética, Instituto de Biociências, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
出版信息
Am J Hum Biol. 2013 Sep-Oct;25(5):702-5. doi: 10.1002/ajhb.22426. Epub 2013 Aug 1.
BACKGROUND
The availability of the full genomes of Homo sapiens, Homo neanderthalensis, and Denisovans, as well as modern bioinformatic tools, are opening new possibilities for the understanding of the differences and similarities present in these taxa.
METHODS
We searched for cognitive genes, examined their status in the genomes of these three entities. All substitutions present among them were retrieved.
RESULTS
We found 93 nonsynonymous substitutions in 51 cognitive genes, in which the derived allele was present in archaic and modern humans and the ancestral allele in other nonhuman primates.
CONCLUSIONS
The general picture obtained is of similarity in cognitive genes between extinct and extant humans.
背景
智人、尼安德特人和丹尼索瓦人的全基因组以及现代生物信息学工具的出现，为理解这些分类群之间的差异和相似性开辟了新的可能性。
方法
我们搜索了认知基因，并检查了它们在这三个实体的基因组中的状态。检索了它们之间存在的所有取代。
结果
我们在 51 个认知基因中发现了 93 个非同义取代，其中衍生等位基因存在于古人类和现代人类中，而祖先等位基因存在于其他非人类灵长类动物中。
结论
获得的总体图像是灭绝的人类和现存的人类在认知基因上的相似性。
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