Kemp I, Dellimore K, Rodriguez R, Scheffer C, Blaine D, Weich H, Doubell A
Department of Mechanical and Mechatronic Engineering, Stellenbosch University, Private Bag X1, Matieland, Stellenbosch, Western Cape Province 7602, South Africa.
Australas Phys Eng Sci Med. 2013 Sep;36(3):363-73. doi: 10.1007/s13246-013-0213-1. Epub 2013 Aug 2.
Experiments performed on a 19 mm diameter bioprosthetic valve were used to successfully validate the fluid-structure interaction (FSI) simulation of an aortic valve at 72 bpm. The FSI simulation was initialized via a novel approach utilizing a Doppler sonogram of the experimentally tested valve. Using this approach very close quantitative agreement (≤12.5%) between the numerical predictions and experimental values for several key valve performance parameters, including the peak systolic transvalvular pressure gradient, rapid valve opening time and rapid valve closing time, was obtained. The predicted valve leaflet kinematics during opening and closing were also in good agreement with the experimental measurements.
在一个直径为19毫米的生物假体瓣膜上进行的实验，成功验证了主动脉瓣在每分钟72次心跳时的流固耦合（FSI）模拟。FSI模拟通过一种新颖的方法初始化，该方法利用实验测试瓣膜的多普勒超声心动图。使用这种方法，在几个关键瓣膜性能参数的数值预测和实验值之间获得了非常接近的定量一致性（≤12.5%），这些参数包括收缩期峰值跨瓣压力梯度、瓣膜快速开启时间和瓣膜快速关闭时间。预测的瓣膜叶在开启和关闭过程中的运动学也与实验测量结果高度一致。
