EMA, Centre LGEI, Ales, France.
Pest Manag Sci. 2013 Nov;69(11):1261-6. doi: 10.1002/ps.3493. Epub 2013 Mar 21.
In 2004, resistance to a commercial formulation of the Cydia pomonella granulovirus (CpGV) was identified in a field population of Cydia pomonella from an organic orchard in southern France. The genetic inheritance of this resistance was analysed in the resistant laboratory strain RGV. This strain was obtained using successive crosses between the resistant field population and a susceptible laboratory strain, SV, with selection for CpGV resistance at each generation.
After eight generations of introgression of the resistant trait into SV, the RGV-8 strain exhibited 7000-fold higher resistance than SV. Mass-crossing experiments showed that resistance to CpGV is strongly dominant, sex dependent and under the control of a single major gene. However, the contribution of other genes is required to explain all of the data obtained in this study. These additional genes do not follow the laws of classical Mendelian transmission.
Transmission of granulovirus resistance in the RGV-8 strain of C. pomonella cannot be fully explained by the effect of a locus located on the Z chromosome. The action of other factors needs to be considered.
2004 年，在法国南部一个有机果园的欧洲梨小食心虫田间种群中发现了对一种商业剂型的苹果实巢蛾核型多角体病毒（CpGV）的抗性。在抗性实验室品系 RGV 中分析了这种抗性的遗传遗传。该品系是通过在每个世代对 CpGV 抗性进行选择，在抗性田间种群和敏感实验室品系 SV 之间进行连续杂交获得的。
在将抗性性状连续 8 代导入 SV 后，RGV-8 菌株的抗性比 SV 高 7000 倍。大量杂交实验表明，对 CpGV 的抗性是强烈的显性，与性别有关，并受单个主基因控制。然而，需要其他基因的贡献来解释本研究中获得的所有数据。这些附加基因不符合经典孟德尔遗传规律。
在欧洲梨小食心虫的 RGV-8 品系中，颗粒病毒抗性的传递不能完全用位于 Z 染色体上的一个基因座的作用来解释。需要考虑其他因素的作用。
