Department of Orthopaedic Surgery, West China Medical School, Sichuan University, West China Hospital, 37# Guoxue Road, Chengdu, Sichuan Province, China.
Bone Joint J. 2013 Aug;95-B(8):1057-63. doi: 10.1302/0301-620X.95B8.31310.
The purpose of this study was to undertake a meta-analysis to determine whether there is lower polyethylene wear and longer survival when using mobile-bearing implants in total knee replacement when compared with fixed-bearing implants. Of 975 papers identified, 34 trials were eligible for data extraction and meta-analysis comprising 4754 patients (6861 knees). We found no statistically significant differences between the two designs in terms of the incidence of radiolucent lines, osteolysis, aseptic loosening or survival. There is thus currently no evidence to suggest that the use of mobile-bearing designs reduce polyethylene wear and prolong survival after total knee replacement.
本研究旨在进行荟萃分析，以确定在全膝关节置换中使用活动衬垫植入物与固定衬垫植入物相比，是否能减少聚乙烯磨损和延长假体生存率。在确定的 975 篇文献中，有 34 项试验符合数据提取和荟萃分析的条件，共纳入 4754 名患者（6861 膝）。我们发现两种设计在透亮线、骨溶解、无菌性松动或生存率方面均无统计学差异。因此，目前尚无证据表明使用活动衬垫设计可减少全膝关节置换术后的聚乙烯磨损并延长假体生存率。
