Rice University.
Blood. 2013 Aug 1;122(5):619-20. doi: 10.1182/blood-2013-06-508481.
In this issue of Blood, Massa et al demonstrated that tumor-tropic bacteria engineered to express specific cancer-related antibodies can recognize and specifically destroy the malignant cells by infecting them with toxic cargo. The findings provide an essential step in establishing the novel approach of enlisting engineered bacteria that speak cancer’s language to outsmart and defeat cancer
在本期《Blood》杂志中，Massa 等人表明，经过基因工程改造、表达特定癌症相关抗体的肿瘤趋向性细菌可以通过感染携带毒性 cargo 的方式识别并特异性地摧毁恶性细胞。这些发现为利用能够识别和攻击肿瘤的工程细菌提供了重要的一步，从而实现了利用癌症语言来智取和击败癌症的新方法。
