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诊断难题:鉴别肉芽肿性多血管炎和结核病。

A diagnostic dilemma: differentiating between granulomatosis with polyangiitis and tuberculosis.

机构信息

North Devon District Hospital, Barnstaple, UK.

出版信息

Clin Med (Lond). 2013 Aug;13(4):411-3. doi: 10.7861/clinmedicine.13-4-411.

DOI:10.7861/clinmedicine.13-4-411
PMID:23908518
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4954315/
Abstract

Granulomatosis with polyangiitis (GPA, formerly Wegener's granulomatosis) can present diagnostic difficulties for the clinician as there can be considerable overlap in features with tuberculosis (TB). Indeed, there are documented cases both of coexisting TB and GPA, and cases wrongly diagnosed as GPA when in fact TB was the underlying diagnosis. This lesson presents a case of GPA where TB was also considered as a differential and highlights the diagnostic and management difficulties when this is the case.

摘要

肉芽肿性多血管炎(GPA,以前称为韦格纳肉芽肿病)可能会给临床医生的诊断带来困难,因为其特征与结核病(TB)有很大的重叠。事实上,既有同时存在 TB 和 GPA 的病例,也有误诊为 GPA 的病例,而实际上基础诊断是 TB。本课程介绍了一例 GPA 病例,当时也考虑了 TB 作为鉴别诊断,并强调了这种情况下的诊断和管理困难。

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Spectrum of anti-neutrophil cytoplasmic antibodies in patients with pulmonary tuberculosis overlaps with that of Wegener's granulomatosis.肺结核患者抗中性粒细胞胞浆抗体谱与韦格纳肉芽肿的抗体谱重叠。
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