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采用计算流体动力学模拟研究狭窄血管的血液动力学特性。

A study on hemodynamic characteristics at the stenosed blood vessel using computational fluid dynamics simulations.

机构信息

Department of Chemical Engineering, Chonbuk National University, Jeonju 561-756, Republic of Korea.

出版信息

J Biomed Nanotechnol. 2013 Jul;9(7):1137-45. doi: 10.1166/jbn.2013.1516.

Abstract

In this study, we have used computational fluid dynamics to investigate the blood flow in the stenosed blood vessels. The numerical simulation using commercial software ADINA 8.6 were solved about the stenosed blood vessel according to the percent of stenosis and Reynolds number. The blood flow in the normal and stenosed blood vessel was grasped for the validity of the model. The characteristic of the pulsatile flow changed through the steady state flow and analysis of the pulsatile flow according to the time was grasped. The computational model with the characteristics of the fluid-structure interaction is introduced to investigate the wall shear stress, pressure distribution and axial flow velocity. The results show that axial flow velocity and wall shear stress in the region of stenosis was increased by increasing percent of stenosis and Reynolds number. Also, we can know that in the stenosed blood vessel the possibility of the generation of the aneurysm was increased by increasing Reynolds number and percent of stenosis.

摘要

在这项研究中,我们使用计算流体动力学来研究狭窄血管中的血流。根据狭窄百分比和雷诺数,使用商业软件 ADINA 8.6 对狭窄血管进行数值模拟。为了验证模型的有效性,我们捕捉了正常和狭窄血管中的血流。通过稳态流和根据时间的脉动流分析,捕捉到脉动流的特征。引入具有流固耦合特性的计算模型,以研究壁面剪切应力、压力分布和轴向流速。结果表明,随着狭窄百分比和雷诺数的增加,狭窄区域的轴向流速和壁面剪切应力增加。此外,我们可以知道,在狭窄的血管中,随着雷诺数和狭窄百分比的增加,动脉瘤的发生可能性增加。

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