获得性免疫缺陷综合征（艾滋病）患者中乙肝表面抗原（HBsAg）、乙肝表面抗体（抗-HBs）及乙肝核心抗体（抗-HBc）的流行情况。
The prevalence of hepatitis B surface antigen (HBsAg), anti-hepatitis B surface (anti-HBs) and anti-hepatitis B core (anti-HBc) in patients with acquired immuno-deficiency syndrome (AIDS).
作者信息
Ogutu E O, Amayo E O, Okoth F, Lule G N
机构信息
Department of Medicine, College of Health Science, University of Nairobi, Kenya.
出版信息
East Afr Med J. 1990 May;67(5):355-8.
Forty one consecutive patients (24 males and 17 females) with AIDS had their blood assayed for HBsAg, anti-HBs and anti-HBc by Reversed Passive Haemagglutination (RPHA), Passive Haemagglutination (PHA) and Enzyme Linked Immunosorbent Assay (ELISA) techniques respectively. 5 (12.2%) were found positive for HBsAg. 10 (24.4%) for anti-HBs and 31 (75.6%) for anti-HBc. 32 (78%) out of 41 patients with AIDS had serological evidence of exposure to hepatitis B virus (HBV). The prevalence of HBsAg found in this study is not different from what has been found in the Kenyan community without AIDS, while that of anti-HBs is much lower than what has been reported in the general community.
连续41例艾滋病患者（24例男性和17例女性）分别采用反向被动血凝试验（RPHA）、被动血凝试验（PHA）和酶联免疫吸附测定（ELISA）技术检测其血液中的乙肝表面抗原（HBsAg）、乙肝表面抗体（抗-HBs）和乙肝核心抗体（抗-HBc）。结果发现5例（12.2%）HBsAg呈阳性，10例（24.4%）抗-HBs呈阳性，31例（75.6%）抗-HBc呈阳性。41例艾滋病患者中有32例（78%）有感染乙型肝炎病毒（HBV）的血清学证据。本研究中发现的HBsAg患病率与在没有艾滋病的肯尼亚人群中发现的患病率没有差异，而抗-HBs的患病率远低于普通人群中报告的患病率。
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