James I M, Hamlyn A N, Brant P C, Hildrew P
J Neurol Neurosurg Psychiatry. 1975 Mar;38(3):214-8. doi: 10.1136/jnnp.38.3.214.
Patients with chronic liver disease, yet without severe encephalopathy, were found to show evidence of increased brain utilization of glucose. The changes were abolished after an intravenous infusion of 15 g ornithine alpha oxoglutarate, given over a period of 15 minutes. The possible implications of these observations are discussed.
患有慢性肝病但无严重肝性脑病的患者被发现有大脑葡萄糖利用增加的证据。在15分钟内静脉输注15克鸟氨酸α-酮戊二酸后,这些变化消失。讨论了这些观察结果可能的意义。