Department of Molecular Medicine and Surgery, Division of Thoracic Surgery, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Ann Thorac Surg. 2013 Aug;96(2):699-701. doi: 10.1016/j.athoracsur.2012.11.061.
Modern extracorporeal membrane oxygenation support has revolutionized the survival outcome of critically ill patients with refractory cardiac failure. Mitral valve replacement in patients treated with extracorporeal membrane oxygenation poses a surgical challenge regarding the choice of appropriate prosthesis. We present two cases of mitral valve bioprosthetic failure within days to weeks after valve replacement. Both patients were supported with extracorporeal membrane oxygenation postoperatively, and the bioprosthetic failure was caused by fusion of the cusps. This mechanism of mitral valve bioprosthetic failure in combination with extracorporeal membrane oxygenation treatment has not previously been described.
体外膜肺氧合支持技术的出现彻底改变了难治性心力衰竭危重症患者的生存结局。体外膜肺氧合支持治疗的患者在二尖瓣置换术中，面临着选择合适假体的挑战。我们报道了两例二尖瓣生物瓣在术后数天至数周内发生故障的病例。这两例患者术后均接受了体外膜肺氧合支持治疗，生物瓣故障是由瓣叶融合引起的。这种体外膜肺氧合治疗相关的二尖瓣生物瓣故障机制尚未有报道。
