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尸检时偶然发现双侧侧脑室黄色肉芽肿——一例报告

Incidental bilateral xanthogranuloma of the lateral ventricles at autopsy--a case report.

作者信息

Moreau Emilie, Lefrancq Thierry, Saint-Martin Pauline

机构信息

Institut Médico-Légal, CHRU de Tours, F-37044 Tours, France.

出版信息

J Forensic Leg Med. 2013 Aug;20(6):647-9. doi: 10.1016/j.jflm.2013.03.039. Epub 2013 Apr 19.

Abstract

We report the case of a woman found dead in a public garden. She had multiple contusions, bruises and lacerations of the face due to blunt force trauma. Microscopic examination of the brain was consistent with a death due to severe craniocerebral injury. The neuropathologist also found yellow nodular lesions located in each lateral ventricle and composed by cholesterol clefts, foamy macrophages, and giant cells. A diagnosis of xanthogranuloma of the choroid plexus was made. According to the literature, xanthogranulomas are uncommon benign lesions of the central nervous system. Mostly are found incidentally at post-mortem examination. However, some of them are symptomatic and can lead to severe nervous central damages if they remain untreated.

摘要

我们报告了一名在公共花园中被发现死亡的女性病例。她因钝器创伤导致面部多处挫伤、瘀伤和撕裂伤。脑部显微镜检查结果与严重颅脑损伤致死相符。神经病理学家还发现每个侧脑室内有黄色结节性病变,由胆固醇裂隙、泡沫巨噬细胞和巨细胞组成。诊断为脉络丛黄色肉芽肿。根据文献,黄色肉芽肿是中枢神经系统罕见的良性病变。大多在尸检时偶然发现。然而,其中一些是有症状的,如果不治疗可能会导致严重的中枢神经损伤。

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