Hamabata Takayuki, Umeda Katsutsugu, Noudomi Seishiro, Daifu Tomoo, Morishima Tatsuya, Saida Satoshi, Hiejima Eitaro, Kato Itaru, Hiramatsu Hidefumi, Watanabe Ken-ichiro, Kurita Akira, Kodama Yuzo, Heike Toshio, Adachi Souichi
Department of Pediatrics, Graduate School of Medicine, Kyoto University.
Rinsho Ketsueki. 2013 Jul;54(7):653-7.
Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) was performed as a diagnostic procedure for two pediatric patients with intra-abdominal tumors. Case 1 was an 8-year-old boy with a huge tumor in the portal-hepatic region. Case 2 was a 17-year-old girl with a history of diabetes and recurrent relapse of Burkitt lymphoma, who had a newly developing tumor in the pancreatic body. In both cases, EUS-FNA was performed as a less invasive diagnostic procedure than open biopsy or total resection of the tumor. Tumor cells were determined to be of the B cell lineage by flow cytometric and immunostaining analyses. Both cases were diagnosed as having Burkitt lymphoma based on detection of IgH/C-MYC translocation by FISH. The aspiration was successfully conducted without severe complications, and both patients were immediately given chemotherapy. EUS-FNA is a safe and minimally invasive procedure with high diagnostic value for pediatric cases with intra-abdominal tumors.
内镜超声引导下细针穿刺活检（EUS-FNA）被用作两名患有腹腔内肿瘤的儿科患者的诊断方法。病例1是一名8岁男孩，在门静脉-肝区有一个巨大肿瘤。病例2是一名17岁女孩，有糖尿病史且伯基特淋巴瘤复发，其胰体部有一个新出现的肿瘤。在这两个病例中，EUS-FNA作为一种比开放性活检或肿瘤全切除侵入性更小的诊断方法进行。通过流式细胞术和免疫染色分析确定肿瘤细胞为B细胞系。基于荧光原位杂交（FISH）检测到IgH/C-MYC易位，这两个病例均被诊断为伯基特淋巴瘤。穿刺成功进行，无严重并发症，两名患者均立即接受化疗。EUS-FNA是一种安全且微创的方法，对患有腹腔内肿瘤的儿科病例具有很高的诊断价值。
