Yenikent State Hospital, Sakarya, Turkey.
J Clin Neurophysiol. 2013 Aug;30(4):411-4. doi: 10.1097/WNP.0b013e31829ddb84.
To analyze the utility of ipsilateral ulnar to median nerve F-wave latency difference in confirmation of ulnar neuropathy at elbow (UNE).
Data of all UNE patients referred to the electroneuromyography laboratory were prospectively collected. Diagnoses were based on the presence of typical symptoms and signs. Motor and sensory conduction studies and F-wave studies were performed on both extremities of all the patients. Ulnar nerve across-elbow motor conduction velocity was calculated for both sides, and an inching test was carried out on symptomatic side. F waves were elicited with 16 supramaximal stimuli and recorded over abductor digiti minimi muscle for ulnar nerve and abductor pollicis brevis muscle for median nerve. Difference between minimum F-wave latency of ulnar nerve and one of median nerve is calculated for each arm. Data of healthy arms were used as control values.
Thirty-four arms of 17 patients with left-sided UNE were included. In all affected arms, minimum F-wave latency of ulnar nerve is longer than one of median nerve (minimum difference, 1.05 milliseconds; maximum difference, 10.9 milliseconds). In all the patients, F-wave latency difference of affected side was greater than one of healthy side. Best cutoff value for F-wave latency difference was calculated as 2.20 milliseconds on detection of UNE. F-wave latency difference was more than 2.20 milliseconds in 16 affected arms, whereas it was more than 2.20 milliseconds in only one healthy arm. Therefore, the sensitivity and specificity were detected as 94.1% and 94.1%, respectively.
Our results revealed that UNE could be confirmed easily with F-wave latency difference studies with a high sensitivity and specificity. This finding should be validated with further studies, which have larger study populations.
分析尺神经到正中神经 F 波潜伏期差在确认肘管尺神经病变(UNE)中的作用。
前瞻性收集所有转至电生理实验室的UNE 患者的数据。诊断基于典型症状和体征。对所有患者的四肢进行运动和感觉传导研究以及 F 波研究。计算双侧肘部尺神经的跨肘运动传导速度,并对症状侧进行逐渐增加刺激测试。用 16 个最大刺激引出 F 波,并记录于小指展肌(尺神经)和拇指短展肌(正中神经)。计算每只手臂的尺神经最小 F 波潜伏期与正中神经最小 F 波潜伏期之差。健康手臂的数据用作对照值。
纳入 17 例左侧 UNE 患者的 34 只手臂。所有受累手臂的尺神经最小 F 波潜伏期均长于正中神经(最小差值为 1.05 毫秒,最大差值为 10.9 毫秒)。在所有患者中,受累侧的 F 波潜伏期差值均大于健侧。检测到 UNE 的最佳 F 波潜伏期差值截断值为 2.20 毫秒。16 只受累手臂的 F 波潜伏期差值大于 2.20 毫秒,而仅一只健康手臂的 F 波潜伏期差值大于 2.20 毫秒。因此,敏感性和特异性分别为 94.1%和 94.1%。
我们的结果表明,F 波潜伏期差值研究可轻松确认 UNE,具有较高的敏感性和特异性。这一发现需要通过更大样本量的进一步研究进行验证。