一名在急诊室出现头痛症状的患者，其临床表现显示出不幸的诊断结果（III级左额叶间变性室管膜瘤伴1p缺失）。
A headache presenting in the emergency room, a clinical manifestation of an unfortunate diagnosis (grade III left frontal anaplastic ependymoma with 1p deletion).
作者信息
Flores-Robles B J, Hurtarte-Sandoval A R, Harrison R M, Cuevas C C
机构信息
Department of Rheumatology Service, Puerta de Hierro Hospital Majadahonda, Madrid, Spain.
出版信息
BMJ Case Rep. 2013 Aug 2;2013:bcr2013010217. doi: 10.1136/bcr-2013-010217.
Abstract
An 18-year-old girl presented with a headache and behavioural changes. She was found to have a frontal mass. Neuroimaging revealed an intra-axial mass, located at the left frontal cortical/subcortical region approximately 6×7, 5×7, 5 cm (TxApxL), having a heterogeneous density with cysts and calcification. She had total gross excision of the neoplasm. Histopathological examination revealed an anaplastic ependymoma. Fluorescence in situ hybridisation, a molecular cytogenetic test, reported deletion of 1p without deletion of 19q. The patient had a good postoperative improvement.
摘要
一名18岁女孩出现头痛和行为改变。她被发现有一个额叶肿块。神经影像学检查发现一个轴内肿块，位于左额叶皮质/皮质下区域，大小约为6×7、5×7、5厘米（前后径×左右径×上下径），密度不均匀，伴有囊肿和钙化。她接受了肿瘤全切术。组织病理学检查显示为间变性室管膜瘤。荧光原位杂交，一种分子细胞遗传学检测，报告1p缺失而19q未缺失。患者术后恢复良好。
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