Kamath Max, Rizvi Maleeha, O'Nions Jenny, Brook Gary
Central Middlesex Hospital, London, UK.
BMJ Case Rep. 2013 Aug 2;2013:bcr2013200309. doi: 10.1136/bcr-2013-200309.
Syphilis is a contagious sexually transmitted infection notable for its complex array of systemic presentations. It is caused by the spirochaete Treponema pallidum and although once considered to be a largely historical condition in the UK, the recent rise in incidence makes syphilis increasingly relevant when considering unusual presentations in at-risk patients. The disease has three stages: primary, secondary and tertiary. The tertiary stage is associated with a plethora of neurological features ranging from psychosis to seizure caused by direct invasion of the spirochaete into the central nervous system. Here we describe the case of a 45-year-old man presenting with tonic clonic seizures on a background of balance and visual problems. Following normal examination and routine investigations further serology confirmed a diagnosis of neurosyphilis. The patient was started on appropriate treatment and made an excellent clinical recovery.
梅毒是一种传染性性传播感染疾病，以其复杂多样的全身症状表现而闻名。它由梅毒螺旋体引起，尽管在英国曾一度被认为主要是一种历史遗留病症，但近期发病率的上升使得在考虑高危患者的异常症状表现时，梅毒变得越来越重要。该疾病有三个阶段：一期、二期和三期。三期梅毒与大量神经系统症状相关，从精神病到由螺旋体直接侵入中枢神经系统引起的癫痫发作。在此，我们描述一例45岁男性患者，其在平衡和视觉问题的背景下出现强直阵挛性癫痫发作。经过常规检查和常规调查，进一步的血清学检查确诊为神经梅毒。该患者开始接受适当治疗，并实现了良好的临床康复。
