Department of Internal Medicine, Section on Infectiology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Clin Infect Dis. 2013 Nov;57(10):1497-9. doi: 10.1093/cid/cit517. Epub 2013 Aug 2.
In this observational cohort study, 10 patients with extensive or treatment-refractory AIDS-associated Kaposi sarcoma were treated with peginterferon alfa-2a. Tumor responses were observed in 9 patients with a median progression-free survival of 645 days. Peginterferon alfa-2a could be an effective therapy for extensive or treatment-resistant Kaposi sarcoma.
在这项观察性队列研究中,10 名广泛或治疗耐药的艾滋病相关性卡波西肉瘤患者接受了聚乙二醇干扰素 alfa-2a 治疗。9 名患者观察到肿瘤缓解,无进展生存期中位数为 645 天。聚乙二醇干扰素 alfa-2a 可能是治疗广泛或耐药性卡波西肉瘤的有效方法。