Department of Pharmacotherapy, University of Utah, 30 South 2000 East, Room 4781, Salt Lake City, UT 84112, USA.
Obesity (Silver Spring). 2013 Jun;21(6):1284-92. doi: 10.1002/oby.20215.
The purpose of this study was to analyze the 1-year cost of cardiovascular (CV) events by body mass index (BMI) subgroups from a US employer health plan perspective.
Patients aged 20-64 years from the GE Centricity Electronic Medical Record, National Health and Nutrition Examination Survey, and MarketScan databases were used to determine prevalence of risk factors (RFs) and CV events and 1-year costs. Risk factors included hypertension (HTN), diabetes, and hyperlipidemia (HLD) and CV events included myocardial infarction, angina, heart failure, and stroke. CV event costs were determined from claims by ICD-9 code in patients with overweight/obesity.
Of 220,136 patients identified in GE, BMI was 25-26.9 in 19.4%, 27-29.9 in 30.4%, 30-34.9 in 27.9%, and ≥35 in 22.3%. Patients with diabetes, HTN, and HLD increased with BMI from 1.8% (25-26.9) to 11.4% (≥35) in males and 1.1% to 6.8% in females. Prevalence of CV events increased from 0.1% with no RFs up to 10.2% with multiple RFs. The average 1-year cost per patient increased from $1122 to $2383 as BMI increased.
Patients with higher BMI values had an increased prevalence of RFs and CV events, which lead to higher average 1-year costs.
本研究旨在从美国雇主健康计划的角度分析体重指数（BMI）亚组的心血管（CV）事件的 1 年成本。
使用来自 GE Centricity 电子病历、全国健康和营养检查调查以及 MarketScan 数据库的 20-64 岁患者，以确定风险因素（RFs）和 CV 事件的流行情况以及 1 年的成本。RFs 包括高血压（HTN）、糖尿病和高脂血症（HLD），CV 事件包括心肌梗死、心绞痛、心力衰竭和中风。超重/肥胖患者通过 ICD-9 代码从索赔中确定 CV 事件的成本。
在 GE 中确定的 220136 名患者中，BMI 在 25-26.9 的占 19.4%，27-29.9 的占 30.4%，30-34.9 的占 27.9%，≥35 的占 22.3%。男性中，患有糖尿病、HTN 和 HLD 的患者比例从 BMI 为 1.8%（25-26.9）增加到 11.4%（≥35），女性中从 1.1%增加到 6.8%。CV 事件的患病率从无 RFs 的 0.1%增加到有多个 RFs 的 10.2%。随着 BMI 的增加，每位患者的平均 1 年成本从 1122 美元增加到 2383 美元。
BMI 值较高的患者 RFs 和 CV 事件的患病率较高，导致平均 1 年成本较高。
