Massaro Peter A, Gajewski Jerzy B, Bailly Greg
Department of Urology, Dalhousie University, Halifax, NS.
Can Urol Assoc J. 2013 Jul-Aug;7(7-8):E462-6. doi: 10.5489/cuaj.204.
We present the outcomes and long-term follow-up of patients who underwent conversion to an ileal conduit urinary diversion using the retubularized patch from the initial augmentation ileocystoplasty.
We reviewed the charts of all patients who underwent this surgery at our centre. The indications for surgery, workup, clinical outcomes and complication rates were assessed. Patient-reported symptom response based on global response assessment (GRA) was determined and used as a subjective measure of overall treatment effectiveness.
Thirteen patients with either bladder pain syndrome/interstitial cystitis (BPS/IC) (n = 11) or neurogenic bladder (n = 2) were followed for a mean of 80 months. The most common indication for surgical conversion was persistent lower urinary tract symptoms (LUTS) or bladder pain. Late complications were frequent, typically low-grade, and usually manageable with conservative therapy; the most common were urinary tract infections (n = 6) and parastomal hernias (n = 5). Two patients developed ureteric strictures. Nine of 13 patients required additional surgery to manage complications or persistent symptoms. Only 5 of 11 GRA respondents reported a successful therapeutic outcome and BPS/IC patients who underwent concurrent cystourethrectomy tended to be most satisfied (2/3). Nevertheless, several patients still achieved symptom control when no other treatment options were available to them.
Conversion to an ileal conduit using the retubularized ileocystoplasty patch offers several technical and therapeutic advantages over creating a urinary diversion from a new bowel segment. It should therefore be considered a viable treatment option in patients who have exhausted more conservative management of their LUTS.
我们报告了那些使用最初扩大回肠膀胱成形术的再管状化补片转为回肠导管尿流改道的患者的治疗结果及长期随访情况。
我们回顾了在我们中心接受该手术的所有患者的病历。评估了手术指征、检查、临床结果及并发症发生率。基于整体反应评估(GRA)确定患者报告的症状反应,并将其用作整体治疗效果的主观衡量指标。
13例膀胱疼痛综合征/间质性膀胱炎(BPS/IC)患者(n = 11)或神经源性膀胱患者(n = 2)接受了平均80个月的随访。手术转为尿流改道最常见的指征是持续性下尿路症状(LUTS)或膀胱疼痛。晚期并发症很常见,通常为轻度,且通常可用保守治疗控制;最常见的是尿路感染(n = 6)和造口旁疝(n = 5)。2例患者出现输尿管狭窄。13例患者中有9例需要额外手术来处理并发症或持续性症状。11例GRA受访者中只有5例报告治疗结果成功,同时接受膀胱尿道切除术的BPS/IC患者往往最满意(2/3)。然而,在没有其他治疗选择的情况下,仍有几名患者实现了症状控制。
使用再管状化回肠膀胱成形术补片转为回肠导管尿流改道比从新的肠段创建尿流改道具有若干技术和治疗优势。因此,对于那些对LUTS进行了更保守治疗但已无效果的患者,应将其视为一种可行的治疗选择。