Kataoka M, Kawamura M, Kimura Y, Itoh H, Tsuda T, Komatsu A, Hamamoto K
Department of Radiology, Ehime University School of Medicine.
Nihon Gan Chiryo Gakkai Shi. 1990 May 20;25(5):1013-8.
Six consecutive patients with unresected gastric lymphoma which were treated by radiation therapy between November, 1976 and March 1989 were reviewed. Radiation therapy was performed using involved fields, total radiation dosages of which ranged from 25.2 to 36 Gy (mean, 29.3 Gy). Five out of the 6 patients were treated with chemotherapy combined with radiation. Regimen of the chemotherapy was CHOP (cyclophosphamide, adriamycin, vincristine and prednisone) in most cases. Three out of the 6 underwent probe laparotomy, but the tumors were diagnosed as unresectable due to locally invading the adjacent structures. They were treated by chemo-radiotherapy and 2 of them are surviving as of the present study (40 and 116 months). The other 3 patients were diagnosed as with clinical stage IV disease and 2 of them were successfully treated with chemo-radiotherapy (21 and 66 months, surviving). These data suggest that unresected gastric lymphomas, which are locally advanced or stage IV disease, are treated by chemoradiotherapy with high curability without any serious complications.
回顾了1976年11月至1989年3月期间接受放射治疗的6例连续性未切除胃淋巴瘤患者。放射治疗采用累及野，总放射剂量为25.2至36 Gy（平均29.3 Gy）。6例患者中有5例接受了化疗联合放疗。化疗方案在大多数情况下为CHOP（环磷酰胺、阿霉素、长春新碱和泼尼松）。6例中有3例接受了探查性剖腹术，但由于肿瘤局部侵犯相邻结构而被诊断为不可切除。他们接受了放化疗，截至本研究时，其中2例仍存活（分别为40个月和116个月）。其他3例患者被诊断为临床IV期疾病，其中2例成功接受了放化疗（分别存活21个月和66个月）。这些数据表明，局部晚期或IV期的未切除胃淋巴瘤通过放化疗治疗具有高治愈率且无任何严重并发症。
