Department of Cardiothoracic Surgery, Rigshospitalet, Copenhagen University Hospital , Copenhagen , Denmark.
Scand Cardiovasc J. 2013 Oct;47(5):303-6. doi: 10.3109/14017431.2013.821625. Epub 2013 Aug 6.
To assess renal outcome in patients discharged from hospital following cardiac surgery-associated acute kidney injury (CSA-AKI) with need for renal replacement therapy.
In April 2012 we conducted a cross-sectional study of patients treated with renal replacement therapy following cardiac surgery during 2008-2010. We included all adult patients with a pre-operative serum creatinine (sCr) < 200 μM, surviving to discharge. Primary endpoint was use of renal replacement therapy after hospital discharge; secondary endpoint was a sCr > 200 μM at the time of follow-up.
We reviewed the records of 3828 patients receiving cardiac surgery in the defined period. A total of 107 adult patients with sCr concentrations < 200 μM were treated with post-operative renal replacement therapy of whom 70 survived to discharge. Fifty-six patients were alive at follow-up and none had required renal replacement therapy after initial discharge. Median sCr concentration at follow-up was 111 [56-257] μM and two patients had sCr above 200 μM.
In this study, renal function recovered in patients discharged from hospital following renal replacement therapy after CSA-AKI. No patients needed further renal replacement therapy and only two (4%) had a sCr > 200 μM at follow-up.
评估因心脏手术后急性肾损伤（CSA-AKI）而需要肾脏替代治疗的出院患者的肾脏结局。
我们于 2012 年 4 月进行了一项回顾性研究，纳入了 2008 年至 2010 年期间心脏手术后接受肾脏替代治疗的患者。纳入标准为术前血清肌酐（sCr）<200μM 且存活至出院的成年患者。主要终点为出院后使用肾脏替代治疗；次要终点为随访时 sCr > 200μM。
我们回顾了该时期内接受心脏手术的 3828 例患者的记录。共有 107 例 sCr 浓度<200μM 的成年患者接受了术后肾脏替代治疗，其中 70 例存活至出院。56 例患者在随访时存活，且无初始出院后需要肾脏替代治疗。随访时 sCr 浓度中位数为 111 [56-257] μM，2 例患者 sCr > 200 μM。
在这项研究中，因 CSA-AKI 接受肾脏替代治疗后出院的患者肾功能恢复。无患者需要进一步的肾脏替代治疗，仅有 2 例（4%）患者在随访时 sCr > 200 μM。
