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肝移植后获得性淀粉样多神经病的可逆性。

Reversibility of acquired amyloid polyneuropathy after liver retransplantation.

机构信息

AP-HP, Hôpital Paul Brousse, Centre Hépato-Biliaire, Villejuif, France; Univ Paris-Sud, UMR-S 785, Villejuif, France; Inserm, Unité 785, Villejuif, France; French National Reference Centre for FAP (NNERF), Le Kremlin Bicêtre, F-94275, France.

出版信息

Am J Transplant. 2013 Oct;13(10):2734-8. doi: 10.1111/ajt.12378. Epub 2013 Aug 5.

DOI:10.1111/ajt.12378
PMID:23915219
Abstract

Domino liver transplantation (DLT) has become an accepted procedure designed to address problems with organ limited supply. However, cases of acquired amyloid neuropathy are increasingly being recognized following this procedure. Until now, only one patient had undergone liver retransplantation and follow-up findings were not reported. We describe the case of a 72-year-old patient with partial recovery from acquired amyloid neuropathy following retransplantation with a deceased donor 7 years after DLT performed for end-stage liver disease. His clinical and paraclinical improvement is described, and the impact of this case on the indication for a domino procedure and the challenges linked to retransplantation are discussed.

摘要

多米诺肝移植(DLT)已成为一种公认的程序,旨在解决器官供应有限的问题。然而,在这种手术后,获得性淀粉样神经病的病例越来越多。到目前为止,只有一名患者接受了肝再移植,并且没有报告随访结果。我们描述了一名 72 岁患者的病例,该患者在因终末期肝病接受 DLT 后 7 年进行了尸体供肝的再次移植,其获得性淀粉样神经病部分恢复。描述了他的临床和辅助检查结果,并讨论了该病例对多米诺程序适应证的影响以及与再次移植相关的挑战。

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引用本文的文献

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Cureus. 2024 Feb 5;16(2):e53605. doi: 10.7759/cureus.53605. eCollection 2024 Feb.
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Treatment With Diflunisal in Domino Liver Transplant Recipients With Acquired Amyloid Neuropathy.二氟尼柳治疗接受多米诺肝移植的获得性淀粉样神经病患者。
Transpl Int. 2022 Apr 13;35:10454. doi: 10.3389/ti.2022.10454. eCollection 2022.
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Domino-liver transplantation: toward a safer and simpler technique in both donor and recipient.
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Updates Surg. 2021 Feb;73(1):223-232. doi: 10.1007/s13304-020-00886-4. Epub 2020 Sep 23.
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Domino Hepatocyte Transplantation: A Therapeutic Alternative for the Treatment of Acute Liver Failure.肝实质细胞移植:急性肝衰竭治疗的一种治疗选择。
Can J Gastroenterol Hepatol. 2018 Jul 2;2018:2593745. doi: 10.1155/2018/2593745. eCollection 2018.
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Iatrogenic amyloid polyneuropathy after domino liver transplantation.多米诺肝移植术后医源性淀粉样多神经病
World J Hepatol. 2017 Jan 28;9(3):126-130. doi: 10.4254/wjh.v9.i3.126.
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FAP neuropathy and emerging treatments.家族性淀粉样多发性神经病变和新兴疗法。
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