AP-HP, Hôpital Paul Brousse, Centre Hépato-Biliaire, Villejuif, France; Univ Paris-Sud, UMR-S 785, Villejuif, France; Inserm, Unité 785, Villejuif, France; French National Reference Centre for FAP (NNERF), Le Kremlin Bicêtre, F-94275, France.
Am J Transplant. 2013 Oct;13(10):2734-8. doi: 10.1111/ajt.12378. Epub 2013 Aug 5.
Domino liver transplantation (DLT) has become an accepted procedure designed to address problems with organ limited supply. However, cases of acquired amyloid neuropathy are increasingly being recognized following this procedure. Until now, only one patient had undergone liver retransplantation and follow-up findings were not reported. We describe the case of a 72-year-old patient with partial recovery from acquired amyloid neuropathy following retransplantation with a deceased donor 7 years after DLT performed for end-stage liver disease. His clinical and paraclinical improvement is described, and the impact of this case on the indication for a domino procedure and the challenges linked to retransplantation are discussed.
多米诺肝移植(DLT)已成为一种公认的程序,旨在解决器官供应有限的问题。然而,在这种手术后,获得性淀粉样神经病的病例越来越多。到目前为止,只有一名患者接受了肝再移植,并且没有报告随访结果。我们描述了一名 72 岁患者的病例,该患者在因终末期肝病接受 DLT 后 7 年进行了尸体供肝的再次移植,其获得性淀粉样神经病部分恢复。描述了他的临床和辅助检查结果,并讨论了该病例对多米诺程序适应证的影响以及与再次移植相关的挑战。