CNRS UMR 5276, Ecole Normale Supérieure de Lyon, 46 Allée d'Italie, 69364 Lyon cedex 07, France.
Biophys Chem. 2013 Dec 15;183:42-56. doi: 10.1016/j.bpc.2013.06.020. Epub 2013 Jul 16.
Microbes often face contrasted and fluctuating environmental conditions, to which they need to adapt or die. Because membranes play a central role in regulating fluxes inward and outward from the cells, maintaining the appropriate structure of the membrane is crucial to maintain cellular integrity and functions. This is achieved in bacteria and eucarya by a modification of the membrane lipid compositions, a strategy termed homeoviscous adaptation. We review here evidence for homeoviscous adaptation in Archaea, and discuss the limits of this strategy and our knowledge in this very peculiar domain of life.
微生物经常面临着对比鲜明且不断变化的环境条件，它们需要适应或死亡。由于膜在调节细胞内外物质通量方面起着核心作用，因此保持膜的适当结构对于维持细胞完整性和功能至关重要。在细菌和真核生物中，通过改变膜脂组成来实现这一点，这种策略被称为同型粘滞适应。我们在这里回顾了古菌中同型粘滞适应的证据，并讨论了这种策略的局限性以及我们在这个非常特殊的生命领域的知识。
