Department of Obstetrics and Gynecology, National Cheng Kung University College of Medicine and Hospital, Tainan, Taiwan.
Taiwan J Obstet Gynecol. 2013 Jun;52(2):258-63. doi: 10.1016/j.tjog.2013.04.018.
An omphalocele, a fetal abdominal defect, is a very important congenital anomaly. Prenatal diagnosis of fetal omphalocele is crucial to clinical management.
To investigate the accuracy of prenatal diagnosis for fetal omphalocele, we undertook a retrospective and consecutive analysis of our ultrasound database between January 1994 and December 2011.
In total, ultrasound (US) detected 52 fetuses with an omphalocele in utero.
The incidence of fetal omphalocele is estimated as 1:1249 (0.08%). We also compared the gestational age at US diagnosis between the two centuries. In the 20(th) century, 22 cases of omphalocele were detected: four (18%) cases at first trimester, 17 (77%) cases at second trimester, and 1 (5%) case at third trimester. In the 21(st) century, 30 cases of omphalocele were detected: 13 (43%) cases at first trimester, 15 (50%) cases at second trimester, and two (7%) cases at third trimester. The gestational age at diagnosis of omphalocele is significantly earlier in the 21(st) century than in the last century.
With the advancement and improvement in US equipment, the early detection of fetal omphalocele is feasible, which will substantially contribute to fetal wellbeing.
脐膨出是一种胎儿腹部缺陷，是一种非常重要的先天性畸形。对胎儿脐膨出的产前诊断对于临床管理至关重要。
为了研究产前诊断胎儿脐膨出的准确性，我们对 1994 年 1 月至 2011 年 12 月期间的超声数据库进行了回顾性连续分析。
共有 52 例胎儿在子宫内被超声检查出患有脐膨出。
胎儿脐膨出的发病率估计为 1:1249（0.08%）。我们还比较了两个世纪的超声诊断孕周。在 20 世纪，发现了 22 例脐膨出：4 例（18%）在孕早期，17 例（77%）在孕中期，1 例（5%）在孕晚期。在 21 世纪，发现了 30 例脐膨出：13 例（43%）在孕早期，15 例（50%）在孕中期，2 例（7%）在孕晚期。21 世纪诊断脐膨出的孕周明显早于上个世纪。
随着超声设备的进步和改进，胎儿脐膨出的早期检测成为可能，这将极大地有助于胎儿的健康。
