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[严重新生儿酸中毒:法国两个围产期中心产科实践的比较与分析]

[Severe neonatal acidosis: comparison and analysis of obstetrical practices in two French perinatal centers].

作者信息

Pommereau-Lathelize J, Maisonneuve E, Jousse M, Guilbaud L, Carbonne B, Pierre F

机构信息

Service de gynécologie obstétrique, CHU de Poitiers, 2, rue de la Milétrie, 86000 Poitiers, France.

Service de gynécologie obstétrique, hôpital Saint-Antoine, université Pierre-et-Marie-Curie, Paris 6, Assistance publique-Hôpitaux de Paris, 75012 Paris, France.

出版信息

J Gynecol Obstet Biol Reprod (Paris). 2014 Apr;43(4):314-21. doi: 10.1016/j.jgyn.2013.06.005. Epub 2013 Jul 31.

Abstract

OBJECTIVES

To identify and compare risk factors for severe neonatal acidosis, defined by an umbilical artery pH inferior to 7.00, and clinical practices in two different perinatal centers.

PATIENTS AND METHODS

In a retrospective study, from 2003 to 2008, in two university perinatal centers (Poitiers and Saint-Antoine in Paris) on all term pregnancies complicated by severe neonatal acidosis (umbilical artery pH<7.00), we elected to compare the following risk factors: maternal characteristics, medical and obstetrical histories, progress of pregnancy, labour and delivery as well as the neonatal status.

RESULTS

Among 23,508 births, 177 term newborns had severe neonatal acidosis. The rate was similar for both perinatal centers of Poitiers and Saint-Antoine (0.92% and 0.77% respectively). Factors associated with severe neonatal acidosis were similar in both centers: maternal age, thick meconium, prior cesarean section. There were differences in obstetrical practices between the two centers: there were more caesarean sections and assisted vaginal deliveries in Paris and more inductions of labour in Poitiers.

CONCLUSION

Severe neonatal acidosis is associated with the geographical origin, the progress of labour and the mode of delivery. It seems that severe neonatal acidosis is unrelated to cesarean delivery.

摘要

目的

识别并比较重度新生儿酸中毒(定义为脐动脉pH值低于7.00)的危险因素,以及两个不同围产期中心的临床实践。

患者与方法

在一项回顾性研究中,于2003年至2008年期间,在两家大学围产期中心(普瓦捷和巴黎的圣安托万)针对所有足月妊娠合并重度新生儿酸中毒(脐动脉pH<7.00)的情况,我们选择比较以下危险因素:母亲特征、医疗和产科病史、妊娠进展、分娩及新生儿状况。

结果

在23,508例分娩中,177例足月新生儿患有重度新生儿酸中毒。普瓦捷和圣安托万这两个围产期中心的发生率相似(分别为0.92%和0.77%)。两个中心与重度新生儿酸中毒相关的因素相似:母亲年龄、胎粪黏稠、既往剖宫产史。两个中心的产科实践存在差异:巴黎剖宫产和阴道助产更多,而普瓦捷引产更多。

结论

重度新生儿酸中毒与地域来源、分娩进展及分娩方式有关。重度新生儿酸中毒似乎与剖宫产无关。

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