Academic Neurology Unit, University of Sheffield, Sheffield, UK.
Seizure. 2013 Nov;22(9):760-5. doi: 10.1016/j.seizure.2013.06.008. Epub 2013 Aug 2.
We have previously reported that one in six patients stops experiencing psychogenic nonepileptic seizures (PNES) following our communication protocol. This prospective multicentre study describes a psycho-educational intervention for PNES building on the initial communication of the diagnosis and examines the feasibility of its delivery by healthcare professionals with minimal experience in psychological therapies.
Three healthcare professionals with minimal training in psychological therapies took part in a one-day training course. 20 participants attended for a four-session manualised psycho-educational intervention delivered at three different clinical neuroscience centres. Participants completed self-report measures prior to the intervention at baseline (n=29) and seven months after diagnosis (n=13) measures included seizure frequency, health related quality of life, healthcare utilisation, activity levels, symptom attributions and levels of functioning. Therapy sessions were audiorecorded and manual adherence assessed.
Of 29 patients enrolled into the study, 20 started and 13 completed the intervention and provided follow-up information. At follow-up, 4/13 of patients had achieved complete seizure control and a further 3/13 reported a greater than 50% improvement in seizure frequency. After training, epilepsy nurses and assistant psychologists demonstrated sufficient adherence to the manualised psycho-educational intervention in 80% of sessions.
The delivery of our brief manualised psycho-educational intervention for PNES by health professionals with minimal training in psychological treatment was feasible. The intervention was associated with higher rates of PNES cessation than those observed in our previous studies describing the short-term outcome of the communication of the diagnosis alone. An RCT of the intervention is justified but a significant proportion of drop-outs will have to be anticipated.
我们之前曾报道,在我们的沟通方案后,六分之一的患者停止经历心因性非癫痫性发作(PNES)。这项前瞻性多中心研究描述了一种基于最初诊断沟通的 PNES 心理教育干预,并检验了由在心理治疗方面经验有限的医疗保健专业人员实施该干预的可行性。
三位在心理治疗方面接受过少量培训的医疗保健专业人员参加了为期一天的培训课程。20 名参与者在三个不同的临床神经科学中心参加了四次基于手册的心理教育干预。参与者在干预前的基线(n=29)和诊断后七个月(n=13)完成了自我报告的测量,包括发作频率、健康相关生活质量、医疗保健利用、活动水平、症状归因和功能水平。治疗会议进行了录音,并评估了手册的遵守情况。
在纳入研究的 29 名患者中,20 名开始并完成了干预并提供了随访信息。在随访时,13 名患者中有 4 名达到了完全发作控制,另有 3 名报告发作频率改善了 50%以上。经过培训,癫痫护士和助理心理学家在 80%的治疗会议中表现出对基于手册的心理教育干预的足够遵守。
由在心理治疗方面接受过少量培训的医疗保健专业人员提供的简短基于手册的心理教育干预对 PNES 的实施是可行的。该干预与更高的 PNES 停止率相关,高于我们之前描述单独沟通诊断的短期结果的研究。该干预的 RCT 是合理的,但预计会有相当比例的患者脱落。