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微创手术经椎间孔腰椎体间融合术后手术节段对患者报告的临床结局的影响:L4-L5 与 L5-S1。

The effect of surgical level on self-reported clinical outcomes after minimally invasive transforaminal lumbar interbody fusion: L4-L5 versus L5-S1.

机构信息

Department of Neurological Surgery, Northwestern University, Chicago, Illinois, USA.

Department of Neurosurgery, Rush University Medical Center, Chicago, Illinois, USA.

出版信息

World Neurosurg. 2014 Jan;81(1):177-82. doi: 10.1016/j.wneu.2013.07.082. Epub 2013 Aug 3.

Abstract

OBJECTIVE

The anatomic and biomechanical aspects of the L5-S1 level present unique operative challenges compared with the L4-L5 level. However, it has not been determined if self-reported outcomes and complications are different between patients treated with a minimally invasive transforaminal lumbar interbody fusion at these specific levels.

METHODS

There were 36 consecutive patients identified who were treated with a minimally invasive transforaminal lumbar interbody fusion procedure. Surgical indications included spondylolisthesis (grade 1 or 2) and degenerative disk disease with associated clinical symptoms. Patients completed a visual analog scale (VAS) for their back and leg and Oswestry Disability Index preoperatively and postoperatively. Outcomes were compared between patients with L4-L5 involvement and patients with L5-S1 involvement. In all patients, fusion was evaluated by dynamic view flexion and extension views at 1 year. In all patients with indeterminate results or incomplete imaging, computed tomography was performed to evaluate for bridging bone and stable hardware positioning.

RESULTS

The surgical indications between the 2 groups were similar (χ(2) = 0.089, df = 2, P = 0.956). There was no significant difference in mean operating time, intraoperative blood loss, and hospital stay (P = 0.937, 0.627, and 0.587). There was no significant difference in the long-term postoperative questionnaire results (P = 0.819 for VAS [back], 0.626 for VAS [leg], and 0.962 for Oswestry Disability Index) or the mean preoperative to postoperative change in Cobb angle (P = 0.626) between the 2 groups. Two complications, one in each group, were a rash from an antibiotic and postoperative nausea.

CONCLUSIONS

Despite differences in biomechanics and unique anatomic challenges at the L5-S1 interspace, there is no difference in self-reported outcomes for patients treated with minimally invasive transforaminal lumbar interbody fusion at the L4-L5 level compared with the L5-S1 level.

摘要

目的

与 L4-L5 相比,L5-S1 水平的解剖和生物力学方面存在独特的手术挑战。然而,尚未确定在这些特定水平接受微创经椎间孔腰椎体间融合术治疗的患者,其报告的结果和并发症是否存在差异。

方法

共确定了 36 例连续接受微创经椎间孔腰椎体间融合术治疗的患者。手术指征包括滑脱(1 或 2 级)和退行性椎间盘疾病伴相关临床症状。患者在术前和术后均使用视觉模拟量表(VAS)评估背部和腿部以及 Oswestry 功能障碍指数。比较 L4-L5 受累患者和 L5-S1 受累患者的结果。在所有患者中,均在术后 1 年时通过动态屈伸位 X 线片评估融合情况。对于结果不确定或影像学不完全的所有患者,均进行 CT 检查以评估桥接骨和稳定的硬件定位。

结果

两组的手术指征相似(χ(2) = 0.089,df = 2,P = 0.956)。两组的平均手术时间、术中失血量和住院时间无显著差异(P = 0.937,0.627 和 0.587)。两组患者的长期术后问卷调查结果(VAS[背部]为 0.819,VAS[腿部]为 0.626,Oswestry 功能障碍指数为 0.962)或术前至术后 Cobb 角的平均变化(P = 0.626)均无显著差异。两组各有 1 例并发症,分别为抗生素引起的皮疹和术后恶心。

结论

尽管 L5-S1 椎间存在生物力学和独特的解剖学挑战,但与 L4-L5 水平相比,接受微创经椎间孔腰椎体间融合术治疗的患者,其报告的结果无差异。

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