Kirienko A I, Karalkin A V, Suleĭmanova M S, Matiushenko A A
Kardiologiia. 1990 May;30(5):45-9.
The study examines the potentialities of using radionuclide methods in the diagnosis of cardiac dysfunctions in chronic post-embolic pulmonary hypertension (CPPH). The most informative parameters are shown to be ejection fraction of the right (RV) and left ventricles (LV), severity of RV hypertrophy and dilation, which show changes in relation to the severity of pulmonary hypertension and the disease length. Radiocardiography employed in CPPH has some limitations. Chronic cor pulmonale decompensation due to CPPH is provided by elevated LV contractility. The stage of decompensation is characterized by signs of myocardial dystrophy and impaired perfusion, as judged from 201Tl myocardial scintigraphy, a sharp fall in RV and LV ejection fraction, severe RV myocardial hypertrophy and its cavity dilation.
该研究探讨了使用放射性核素方法诊断慢性栓塞后肺动脉高压（CPPH）所致心脏功能障碍的可能性。结果显示，最具信息量的参数是右心室（RV）和左心室（LV）的射血分数、RV肥厚和扩张的严重程度，这些参数随肺动脉高压的严重程度和疾病病程而变化。CPPH中使用的放射心动图有一些局限性。CPPH所致慢性肺心病失代偿是由LV收缩力升高引起的。根据201Tl心肌闪烁显像判断，失代偿期的特征是心肌营养不良和灌注受损的迹象、RV和LV射血分数急剧下降、严重的RV心肌肥厚及其腔室扩张。
