Department of Internal Medicine, Department of Internal Medicine, University of Iowa Hospitals and Clinics, Iowa City, IA.
Department of Internal Medicine, Department of Internal Medicine, University of Iowa Hospitals and Clinics, Iowa City, IA.
Chest. 2013 Aug;144(2):666-669. doi: 10.1378/chest.12-2129.
Urate nephropathy is observed primarily in patients treated for malignancy, but several other predisposing conditions are recognized. We report a case in which urate nephropathy complicated status epilepticus and review the literature regarding previous similar cases. In addition, we discuss current views of the pathophysiology of acute kidney injury due to urate nephropathy. This case illustrates the value of carefully examining the urine of patients with acute kidney injury to identify causes that may have a specific treatment.
尿酸肾病主要见于接受恶性肿瘤治疗的患者，但也存在其他几种易患情况。我们报告了一例尿酸肾病并发癫痫持续状态的病例，并对之前类似病例的文献进行了回顾。此外，我们还讨论了尿酸肾病引起的急性肾损伤的病理生理学的当前观点。该病例说明了仔细检查急性肾损伤患者尿液以识别可能有特定治疗方法的原因的重要性。
