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马兜铃酸蜂蜜中毒酷似急性心肌梗死。

Mad honey poisoning mimicking acute myocardial infarction.

机构信息

Toxicology Reference Laboratory, Princess Margaret Hospital, Laichikok, Hong Kong.

出版信息

Hong Kong Med J. 2013 Aug;19(4):354-6. doi: 10.12809/hkmj133936.

DOI:10.12809/hkmj133936
PMID:23918513
Abstract

We report a case of acute poisoning in a 48-year-old man who presented with chest pain, abdominal pain, dizziness, sweatiness, blurred vision, and severe hypotension after ingestion of honey. His electrocardiogram showed sinus bradycardia and transient ST elevation. He made a good recovery after treatment with atropine and close monitoring. Grayanotoxin was detected in his urine and the honey he ingested, which confirmed a diagnosis of mad honey poisoning. This is a condition prevalent in the Black Sea region around Turkey but rarely seen locally. Although mad honey poisoning is life-threatening, early use of atropine is life-saving. Such poisoning may present with ST elevation in the electrocardiogram and symptoms mimicking acute myocardial infarction. It is therefore essential for clinicians to recognise this unusual form of poisoning and avoid the disastrous use of thrombolytic therapy.

摘要

我们报告了一例 48 岁男性急性中毒病例,该患者在摄入蜂蜜后出现胸痛、腹痛、头晕、出汗、视力模糊和严重低血压。他的心电图显示窦性心动过缓和一过性 ST 段抬高。经阿托品治疗和密切监测后,他恢复良好。他的尿液和所摄入的蜂蜜中检测到格尼泊毒素,这证实了他患有疯蜜中毒。这种情况在土耳其周围的黑海地区很常见,但在当地很少见。尽管疯蜜中毒有生命危险,但早期使用阿托品是救命的。这种中毒可能会出现心电图 ST 段抬高和类似急性心肌梗死的症状。因此,临床医生必须认识到这种不常见的中毒形式,并避免灾难性地使用溶栓治疗。

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Mad honey poisoning mimicking acute myocardial infarction.马兜铃酸蜂蜜中毒酷似急性心肌梗死。
Hong Kong Med J. 2013 Aug;19(4):354-6. doi: 10.12809/hkmj133936.
2
An unusual presentation of mad honey poisoning: acute myocardial infarction.疯蜜中毒的一种不寻常表现:急性心肌梗死。
Int J Cardiol. 2008 Sep 26;129(2):e56-8. doi: 10.1016/j.ijcard.2007.06.129. Epub 2007 Sep 24.
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Hypotension, bradycardia and syncope caused by honey poisoning.蜂蜜中毒引起的低血压、心动过缓和晕厥。
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Mad-honey sexual activity and acute inferior myocardial infarctions in a married couple.一对已婚夫妇因食用疯蜜出现性活动及急性下壁心肌梗死
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Clinical characteristics and outcomes of patients with grayanotoxin poisoning after the ingestion of mad honey from Nepal.尼泊尔疯蜜中毒致灰藜毒素中毒患者的临床特征及预后
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Clinical review of grayanotoxin/mad honey poisoning past and present.灰藜毒素/疯蜜中毒的临床回顾:过去与现在
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Atrioventricular block induced by mad-honey intoxication: confirmation of diagnosis by pollen analysis.疯蜜中毒诱发的房室传导阻滞:通过花粉分析确诊
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引用本文的文献

1
Clinical Presentation, Electrocardiographic Findings, and Factors Related to the Hospitalization In Mad-Honey Intoxication.疯蜜中毒的临床表现、心电图表现及与住院相关的因素
Sisli Etfal Hastan Tıp Bul. 2022 Sep 22;56(3):365-374. doi: 10.14744/SEMB.2022.45144. eCollection 2022.
2
Mad honey: uses, intoxicating/poisoning effects, diagnosis, and treatment.疯蜜:用途、中毒效应、诊断及治疗
RSC Adv. 2018 May 22;8(33):18635-18646. doi: 10.1039/c8ra01924j. eCollection 2018 May 17.
3
Type 2 myocardial infarction after ingestion of mad honey in a patient with normal coronary arteries.
一名冠状动脉正常的患者摄入疯蜜后发生2型心肌梗死。
Korean J Intern Med. 2015 Jul;30(4):540-2. doi: 10.3904/kjim.2015.30.4.540. Epub 2015 Jun 29.