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促使准父母接受 Tdap 疫苗接种。

Engaging expectant parents to receive Tdap vaccination.

机构信息

School of Medicine, Duke University, Durham, North Carolina.

出版信息

Am J Perinatol. 2014 May;31(5):407-12. doi: 10.1055/s-0033-1352483. Epub 2013 Aug 5.

DOI:10.1055/s-0033-1352483
PMID:23918521
Abstract

OBJECTIVE

To assess the acceptability of a Tdap vaccination program for partners of pregnant women.

STUDY DESIGN

Pregnant women and their partners were enrolled in a prospective acceptability study. For partners absent during the initial encounter, an introductory letter inviting the partner to participate was sent home. Tetanus and diphtheria toxoids and acellular pertussis vaccine (Tdap) was offered to vaccine-eligible partners while vaccine-eligible pregnant women were offered Tdap immediately postpartum, as per national recommendations at the time the study was conducted. Tdap acceptance was defined as vaccination during study participation.

RESULTS

A total of 69 pregnant women and 63 partners were enrolled. Excluding the 19 partners reporting prior receipt, 61.4% of partners (27/44) accepted Tdap during the study. Those who enrolled following the introductory letter were more likely to accept Tdap than those enrolled at the initial encounter (84 vs. 44%, p = 0.005). Excluding the 29 pregnant women reporting prior receipt, 65% (26/40) received Tdap postpartum. Demographic factors and vaccine beliefs were not associated with Tdap acceptance.

CONCLUSION

Tdap vaccination for partners of pregnant women during prenatal care is acceptable. Large-scale implementation would require substantial interest and willingness of obstetrician-gynecologists to administer Tdap not only to pregnant women but also to their partners. Such a program would provide improved "cocooning" of vulnerable infants against pertussis.

摘要

目的

评估为孕妇的伴侣接种 Tdap 疫苗的可接受性。

研究设计

孕妇及其伴侣参加了一项前瞻性可接受性研究。对于在初次就诊时不在场的伴侣,会寄回家一封邀请伴侣参与的介绍信。根据当时研究进行时的国家建议,为有资格接种疫苗的伴侣提供破伤风、白喉类毒素和无细胞百日咳疫苗(Tdap),而有资格接种疫苗的孕妇则在产后立即接种 Tdap。Tdap 的接受程度定义为在研究参与期间接种疫苗。

结果

共纳入 69 名孕妇和 63 名伴侣。排除报告先前接种的 19 名伴侣后,44 名伴侣中有 61.4%(27/44)在研究期间接受了 Tdap。那些在收到介绍信后注册的人比那些在初次就诊时注册的人更有可能接受 Tdap(84 比 44%,p=0.005)。排除报告先前接种的 29 名孕妇后,40 名孕妇中有 65%(26/40)在产后接种了 Tdap。人口统计学因素和疫苗信念与 Tdap 的接受程度无关。

结论

在产前保健期间为孕妇的伴侣接种 Tdap 是可以接受的。大规模实施需要妇产科医生对 Tdap 有很大的兴趣和意愿,不仅要为孕妇接种,还要为她们的伴侣接种。这样的计划将为脆弱婴儿提供更好的百日咳“保护”。

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引用本文的文献

1
Tdap vaccine attitudes and utilization among pregnant women from a high-risk population.高危人群中孕妇对破伤风类毒素、白喉和无细胞百日咳(Tdap)疫苗的态度及接种情况
Hum Vaccin Immunother. 2016 Apr 2;12(4):872-8. doi: 10.1080/21645515.2015.1094594. Epub 2015 Oct 2.
2
Vaccinations for pregnant women.孕妇疫苗接种。
Obstet Gynecol. 2015 Jan;125(1):212-226. doi: 10.1097/AOG.0000000000000581.