Dandale Ameet, Dhurat Rachita, Ghate Smita
Department of Dermatology, Lokmanya Tilak Municipal Medical College and Hospital, Mumbai, India.
Indian J Sex Transm Dis AIDS. 2013 Jan;34(1):44-6. doi: 10.4103/0253-7184.112939.
Perianal pseudoverrucous papules and nodules (PPPN) is a rare entity attributed to chronic irritation. We came across this entity in a case of spina bifida. A 14 year old girl having spina bifida at L3 presented with complaints of multiple asymptomatic whitish lesions on the inner aspect of thighs and labia majora since early childhood. She had incontinence of stool and urine since birth. Cutaneous examination revealed multiple 3-12 mm flat topped moist papules, few verrucous nodules, some of these lesions coalesced to form plaques at the perianal area extending upto the labia majora. On histology marked epidermal hyperplasia and pale keratinocytes in the epidermis was seen. This confirmed the diagnosis of PPPN. This rare condition can be mistaken with sexually transmitted diseases leading to unnecessary investigations and treatment.
肛周假性疣状丘疹和结节（PPPN）是一种罕见的因慢性刺激引起的病症。我们在一例脊柱裂病例中遇到了这种情况。一名14岁L3水平脊柱裂的女孩自幼年起就出现大腿内侧和大阴唇内侧多个无症状白色病变的主诉。她自出生以来就有大小便失禁。皮肤检查发现多个3 - 12毫米的平顶湿润丘疹、少数疣状结节，其中一些病变融合形成斑块，位于肛周区域并延伸至大阴唇。组织学检查可见表皮明显增生以及表皮内苍白的角质形成细胞。这证实了PPPN的诊断。这种罕见病症可能会被误诊为性传播疾病，从而导致不必要的检查和治疗。
