Fuhr Peter, Gschwandtner Ute, Brunnschweiler Heiner, Taub Ethan
Neurologische Klinik, Universitätsspital Basel, Basel, Switzerland.
Praxis (Bern 1994). 2013 Aug 7;102(16):981-5. doi: 10.1024/1661-8157/a001375.
Correct diagnosis is the main problem at the beginning of Parkinson's disease. Treatment is symptomatic and begins with levodopa or dopamine agonists, depending on age and neuropsychiatric symptoms. When many drug intakes are necessary or major non-motor problems are present, the situation becomes complex and requires individual treatment plans including non-pharmacological therapies. Deep brain stimulation is an option when a satisfactory mobility cannot be reached without inacceptable side effects.
正确诊断是帕金森病初期的主要问题。治疗是对症治疗,根据年龄和神经精神症状,从左旋多巴或多巴胺激动剂开始。当需要多次服药或存在严重的非运动问题时,情况会变得复杂,需要包括非药物治疗在内的个体化治疗方案。当不出现不可接受的副作用就无法达到满意的运动能力时,深部脑刺激是一种选择。