Stein E, Sedlacek T, Fabian R L, Nishioka N S
Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston.
Lasers Surg Med. 1990;10(4):384-8. doi: 10.1002/lsm.1900100412.
A pulsed holmium laser transmitted through a quartz fiber was used to create osteotomies in the facial bones and sinuses of rabbits. The ablation process was quantified and residual thermal injury was assessed by light microscopy. Adjacent thermal damage was determined to vary between 130 and 220 microns and was independent of radiant exposure and pulse repetition rate. In other studies, large osteotomies were made to examine the biological response and to assess the technical feasibility of using fiber-delivered laser pulses in an operative setting. The animals tolerated the procedure without obvious problems and postoperative follow-up revealed a vigorous healing response. Because it can ablate both bone and soft tissue and can be transmitted through readily available, flexible quartz fibers, the holmium laser may prove to be a useful adjunct to endoscopic sinus surgical procedures.
使用通过石英纤维传输的脉冲钬激光在兔面部骨骼和鼻窦中制造截骨术。通过光学显微镜对消融过程进行量化，并评估残余热损伤。确定相邻热损伤在130至220微米之间变化，且与辐射暴露和脉冲重复率无关。在其他研究中，进行大的截骨术以检查生物学反应，并评估在手术环境中使用光纤传输激光脉冲的技术可行性。动物耐受该手术且无明显问题，术后随访显示愈合反应良好。由于钬激光既能消融骨组织又能消融软组织，且可通过 readily available、柔性石英纤维传输，因此钬激光可能被证明是内窥镜鼻窦手术的有用辅助工具。 （原文中“readily available”直译为“随时可用的”，这里意译为“容易获得的”更符合语境）
