Department of chemistry, Shahid Beheshti University, Tehran 1983963113 (Iran), Fax: (+98) 21-22431661.
Chemistry. 2013 Sep 9;19(37):12553-9. doi: 10.1002/chem.201301175. Epub 2013 Aug 6.
We have developed an organocatalytic modified Feist-Bénary reaction of cyclic dicarbonyl compounds, isatins and cyclic α-bromo dicarbonyl compounds. This method affords bisspirooxindole-fused dihydrofurans containing two vicinal spiro centers. To the best of our knowledge, employing cyclic α-halo dicarbonyl compounds for the synthesis of bisspirooxindole-fused dihydrofurans has not been previously reported.
我们开发了一种有机催化的改性 Feist-Bénary 反应，用于环状二羰基化合物、色酮和环状α-溴代二羰基化合物。该方法提供了含有两个相邻手性中心的双螺环氧化吲哚并二氢呋喃。据我们所知，以前从未报道过使用环状α-卤代二羰基化合物来合成双螺环氧化吲哚并二氢呋喃。
