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Niacin has been used for years to treat hypercholesterolemia, but may not be as beneficial as thought for patients at high risk of cardiovascular disease. Until further research is done, niacin should be used only in patients who do not tolerate or respond to statin therapy, and never in patients who have achieved goal LDL cholesterol on a statin.

烟酸多年来一直用于治疗高胆固醇血症，但对于心血管疾病高危患者而言，其益处可能并不像人们认为的那样大。在进行进一步研究之前，烟酸仅应用于不耐受他汀类药物治疗或对他汀类药物治疗无反应的患者，绝不能用于使用他汀类药物已使低密度脂蛋白胆固醇达到目标值的患者。