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微创经皮肾镜取石术治疗单纯和复杂肾盏结石:超过 10000 例病例的对比分析。

Minimally invasive percutaneous nephrolithotomy for simple and complex renal caliceal stones: a comparative analysis of more than 10,000 cases.

机构信息

Department of Urology, Minimally Invasive Surgery Center, The First Affiliated Hospital of Guangzhou Medical University , and Guangdong Key Laboratory of Urology, Guangzhou, Guangdong Province, China .

出版信息

J Endourol. 2013 Oct;27(10):1203-8. doi: 10.1089/end.2013.0061.

Abstract

PURPOSE

To determine whether minimally invasive PCNL (MPCNL) is as safe and effective in the management of complex renal caliceal stones as it is for simple renal stones.

PATIENTS AND METHODS

We retrospectively reviewed 5761(41.2%) simple caliceal stones (isolated renal pelvis including isolated calix) and 8223 (58.8%) complex caliceal stones (renal pelvis accompanying two calices at least) that were managed by MPCNL between 1992 nd 2011. The safety, efficacy, and outcome were compared and analyzed.

RESULTS

Stone burden was larger in complex caliceal stones (1763.0 vs 1018.6 mm(2), P<0.05). Patients with simple stones had significantly shorter operative time, less frequency of multiple percutaneous accesses, and less hemoglobin drop. They also had a higher initial stone-free rate (SFR) (77.6% vs 66.4%) after a single session of MPCNL (P<0.05). The differences diminished in the final SFR (86.7% vs 86.1%) after relook and/or auxiliary procedures (P>0.05). The complication rate (17.9% vs 19.0%) and blood transfusion rate (grade II) (2.2% vs 3.2%) were similar in both groups (P>0.05). Both groups had a low rate of high Clavien grade complications. Renal vascular embolizations (grade III), however, were significantly higher in patients with complex caliceal stones (P<0.05).

CONCLUSIONS

MPCNL is a safe and effective treatment option for patients with complex caliceal stones except there is a slightly higher frequency rate of embolization. There was a higher initial SFR in simple stones, but this difference diminished with secondary procedures.

摘要

目的

探讨微创经皮肾镜取石术(MPCNL)治疗复杂性肾盂肾盏结石的安全性和有效性是否与治疗单纯性肾盂肾盏结石相同。

方法

回顾性分析 1992 年至 2011 年期间采用 MPCNL 治疗的 5761 例(41.2%)单纯肾盂肾盏结石(单纯肾盂包括单纯肾盏)和 8223 例(58.8%)复杂性肾盂肾盏结石(肾盂伴至少两个肾盏)。比较分析安全性、有效性和治疗结果。

结果

复杂性肾盂肾盏结石的结石负荷较大(1763.0 比 1018.6mm²,P<0.05)。单纯性结石患者的手术时间明显缩短,多次经皮肾穿刺的频率较低,血红蛋白下降幅度较小。单次 MPCNL 后初始结石清除率(SFR)也较高(77.6%比 66.4%,P<0.05)。再次探查和/或辅助治疗后,最终 SFR(86.7%比 86.1%)的差异减小(P>0.05)。两组并发症发生率(17.9%比 19.0%)和输血率(Ⅱ级)(2.2%比 3.2%)相似(P>0.05)。两组均有较低的高 Clavien 分级并发症发生率。然而,复杂性肾盂肾盏结石患者的肾血管栓塞(Ⅲ级)发生率明显较高(P<0.05)。

结论

MPCNL 是治疗复杂性肾盂肾盏结石的安全有效的治疗方法,除栓塞发生率略高外。单纯性结石初始 SFR 较高,但随着二次手术,这种差异会减小。

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