Gelaw Yeshigeta, Asaminew Tsedeke
Department of Ophthalmology, College of Public Health and Medical Sciences, Jimma University, PO Box: 440, Jimma, Ethiopia.
BMC Res Notes. 2013 Aug 7;6:313. doi: 10.1186/1756-0500-6-313.
Anthrax is a zoonotic disease caused by Bacillus anthracis. Naturally occurring human infection is rare and is generally the result of contact with anthrax-infected animals or animal products.
We examined three patients who had contact with presumed anthrax-infected animal and/or its product and presented with preseptal cellulitis with a localized itchy erythematous papule of the eyelid and non-pitting periorbital edema, followed by ulceration and dark eschar formation. All the three patients responded to intravenous antibiotics, and the lesion resolved leaving scars which caused cicatricial ectropion in all cases.
Anthrax is a rare disease but should be considered in the differential diagnosis of ulcerative (and eschar forming) preseptal cellulitis with a history of contact with anthrax-infected animals or animal products. Furthermore, cicatrization of the eyelids, one of the sequelae of periocular cutaneous anthrax, should be addressed. Urgent case report to the local zoonotic disease and infection control body and other responsible authorities is recommended.
炭疽是由炭疽杆菌引起的一种人畜共患病。自然发生的人类感染较为罕见,通常是接触感染炭疽的动物或动物产品所致。
我们检查了三名接触过疑似感染炭疽的动物和/或其产品的患者,他们表现为睑前蜂窝织炎,伴有眼睑局限性瘙痒性红斑丘疹和非凹陷性眶周水肿,随后出现溃疡和黑色焦痂形成。所有三名患者对静脉用抗生素均有反应,病变消退后留下瘢痕,所有病例均导致瘢痕性睑外翻。
炭疽是一种罕见疾病,但在鉴别诊断有接触感染炭疽动物或动物产品史的溃疡性(和焦痂形成性)睑前蜂窝织炎时应予以考虑。此外,眼周皮肤炭疽的后遗症之一眼睑瘢痕化问题也应得到解决。建议紧急向当地人畜共患病和感染控制机构及其他相关部门报告病例。