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[Resistance profile of rilpivirine].[利匹韦林的耐药谱]
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J Med Virol. 2014 Sep;86(9):1459-66. doi: 10.1002/jmv.23978. Epub 2014 May 17.
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Prevalence of TMC278 (rilpivirine) associated mutations in the Frankfurt Resistance Database.法兰克福耐药数据库中 TMC278（利匹韦林）相关突变的流行率。
J Clin Virol. 2012 Mar;53(3):248-50. doi: 10.1016/j.jcv.2011.12.012. Epub 2011 Dec 30.

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Sub-Epidemics Explain Localized High Prevalence of Reduced Susceptibility to Rilpivirine in Treatment-Naive HIV-1-Infected Patients: Subtype and Geographic Compartmentalization of Baseline Resistance Mutations.亚流行情况解释了初治HIV-1感染患者中对利匹韦林敏感性降低的局部高流行率：基线耐药突变的亚型和地理分区
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Factors influencing the efficacy of rilpivirine in HIV-1 subtype C in low- and middle-income countries.影响rilpivirine在低收入和中等收入国家的HIV-1 C型病毒中疗效的因素。
J Antimicrob Chemother. 2016 Feb;71(2):367-71. doi: 10.1093/jac/dkv359. Epub 2015 Oct 30.

本文引用的文献

1
FDA notifications. Complera approved.美国食品药品监督管理局通知。Complera已获批。
AIDS Alert. 2011 Nov;26(11):130-1.
2
2011 update of the drug resistance mutations in HIV-1.2011年人类免疫缺陷病毒1型耐药性突变的更新情况
Top Antivir Med. 2011 Nov;19(4):156-64.
3
Genotypic and phenotypic characterization of HIV-1 isolates obtained from patients on rilpivirine therapy experiencing virologic failure in the phase 3 ECHO and THRIVE studies: 48-week analysis.在 ECHO 和 THRIVE 研究的 3 期临床试验中，接受利匹韦林治疗但病毒学失败的患者中分离到的 HIV-1 病毒株的基因型和表型特征：48 周分析。
J Acquir Immune Defic Syndr. 2012 Jan 1;59(1):39-46. doi: 10.1097/QAI.0b013e31823df4da.
4
Rilpivirine versus efavirenz with tenofovir and emtricitabine in treatment-naive adults infected with HIV-1 (ECHO): a phase 3 randomised double-blind active-controlled trial. rilpivirine 与 efavirenz 联合替诺福韦和恩曲他滨治疗 HIV-1 感染初治成人患者（ECHO）：一项 3 期随机双盲阳性对照临床试验。
Lancet. 2011 Jul 16;378(9787):238-46. doi: 10.1016/S0140-6736(11)60936-7.
5
Rilpivirine versus efavirenz with two background nucleoside or nucleotide reverse transcriptase inhibitors in treatment-naive adults infected with HIV-1 (THRIVE): a phase 3, randomised, non-inferiority trial. rilpivirine 与依非韦伦联合两种背景核苷（酸）逆转录酶抑制剂治疗初治 HIV-1 感染成人（THRIVE）：一项 3 期、随机、非劣效性试验。
Lancet. 2011 Jul 16;378(9787):229-37. doi: 10.1016/S0140-6736(11)60983-5.
6
Low-frequency HIV-1 drug resistance mutations and risk of NNRTI-based antiretroviral treatment failure: a systematic review and pooled analysis.低频 HIV-1 耐药突变与 NNRTI 为基础的抗逆转录病毒治疗失败风险：系统评价和汇总分析。
JAMA. 2011 Apr 6;305(13):1327-35. doi: 10.1001/jama.2011.375.
7
HIV-1 drug resistance mutations among antiretroviral-naive HIV-1-infected patients in Asia: results from the TREAT Asia Studies to Evaluate Resistance-Monitoring Study.亚洲初治 HIV-1 感染者的抗逆转录病毒药物耐药性突变：来自 TREAT Asia 耐药监测研究的结果。
Clin Infect Dis. 2011 Apr 15;52(8):1053-7. doi: 10.1093/cid/cir107.
8
Cohort profile: The PharmAccess African (PASER-M) and the TREAT Asia (TASER-M) monitoring studies to evaluate resistance--HIV drug resistance in sub-Saharan Africa and the Asia-Pacific.队列简介：PharmAccess非洲（PASER-M）和亚太地区治疗（TASER-M）监测研究，以评估撒哈拉以南非洲和亚太地区的耐药性——艾滋病毒耐药性。
Int J Epidemiol. 2012 Feb;41(1):43-54. doi: 10.1093/ije/dyq192. Epub 2010 Nov 10.
9
Scale-up of national antiretroviral therapy programs: progress and challenges in the Asia Pacific region.国家抗逆转录病毒治疗方案的扩展：亚太地区的进展和挑战。
AIDS. 2010 Sep;24 Suppl 3:S62-71. doi: 10.1097/01.aids.0000390091.45435.ea.
10
Antiretroviral therapy in AIDS patients with CMV disease: impact on the survival and long-term treatment outcome.艾滋病合并巨细胞病毒病患者的抗逆转录病毒治疗：对生存及长期治疗结局的影响
J Infect. 2008 Jan;56(1):40-3. doi: 10.1016/j.jinf.2007.10.005. Epub 2007 Nov 26.

Rilpivirine resistance-associated mutations among antiretroviral-naive patients infected with HIV-1 in Asia.

作者信息

Sungkanuparph Somnuek, Jiamsakul Awachana, Kiertiburanakul Sasisopin, Sirivichayakul Sunee, Praparattanapan Jutarat, Kantor Rami

出版信息

J Acquir Immune Defic Syndr. 2013 Mar 1;62(3):e98-100. doi: 10.1097/QAI.0b013e31827a34b2.

DOI:10.1097/QAI.0b013e31827a34b2
PMID:23924642
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3738917/
Abstract
摘要