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厄瓜多尔亚热带地区的皮肤利什曼病“chiclero 的溃疡”。

Cutaneous leishmaniasis "chiclero's ulcer" in subtropical Ecuador.

出版信息

Am J Trop Med Hyg. 2013 Aug;89(2):195-196. doi: 10.4269/ajtmh.12-0690.

Abstract

An 18-year-old female presented with a severe ulcerative lesion on her right ear of 6 weeks duration. Her right ear was edematous and erythematous with a large, painless ulcerative lesion covering a third of the pinna and satellite papular lesions on the posterior. She was diagnosed with chiclero's ulcer. A skin smear stained with Diff-quik showed abundant Leishmania parasites. Chiclero's ulcer is a rare clinical presentation and is typically severe and difficult to treat. Physicians in Ecuador recommend administering prolonged intramuscular Glucantime. Side effects are common and can be severe resulting in low patient compliance. Because of preferences of the patient and the large volume needed for her weight, we recommended topical treatment with a lotion of Glucantime mixed half and half with white Merthiolate. After applying this lotion to the lesion 3 to 4 times a day for 6 weeks, the lesion healed.

摘要

一位 18 岁女性,右侧耳部出现一严重溃疡性损害,病程 6 周。右侧耳部肿胀、红斑,有一大型无痛性溃疡性损害,累及耳轮 1/3,其后侧有卫星状丘疹性损害。她被诊断为恰卡里溃疡。耳郭溃疡处皮肤直接涂片,用 Diff-Quick 染色,显示有丰富的利什曼原虫。恰卡里溃疡是一种罕见的临床表现,通常较为严重且难以治疗。厄瓜多尔的医生建议采用肌肉注射葡萄糖酸锑钠进行长期治疗。该药物副作用常见且可能较为严重,导致患者顺应性较差。由于患者的个人意愿和她的体重所需的大量药物,我们建议使用葡萄糖酸锑钠和白降汞按 1:1 混合的洗剂进行局部治疗。每天将这种洗剂涂于皮损处 3 到 4 次,持续 6 周后,皮损愈合。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6324/3741233/7a6dd3ad58a5/tropmed-89-195-g001.jpg

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