利用 DNA 固定化谐振器对自聚集单壁碳纳米管进行高灵敏度检测。
Highly sensitive detection of self-aggregated single-walled carbon nanotubes using a DNA-immobilized resonator.
机构信息
Department of Mechanical Engineering, Korea University, Seoul 136-701, Republic of Korea.
出版信息
Chem Commun (Camb). 2013 Oct 7;49(77):8635-7. doi: 10.1039/c3cc42911c.
PMID:23926595
Abstract
By using DNA linkers, we are able to conjugate self-crosslinked SWNTs which could be detected upon hybridization with a DNA immobilized resonator. The DNA immobilized resonator is able to detect SWNTs with a detection limit of 10 ng ml(-1) which was 2-3 orders of magnitude smaller than the reported SWNT toxicity concentration.
摘要
通过使用 DNA 接头，我们能够连接自交联的单壁碳纳米管，这些单壁碳纳米管在与固定在谐振器上的 DNA 杂交时可以被检测到。固定在谐振器上的 DNA 能够检测到浓度低至 10ng/ml 的单壁碳纳米管，这比报道的单壁碳纳米管毒性浓度低 2-3 个数量级。
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