Genesis Laboratories, Inc., Wellington, CO 80549, USA.
J Med Entomol. 2013 Jul;50(4):833-7.
Visceral Leishmaniasis (VL) is a vector-borne disease endemic to the Indian subcontinent. The Phlebotomus genus of sand flies is the vector for VL in the Old World, with the vector on the Indian Subcontinent being Phlebotomus argentipes. Cattle are a commodity in this region and a frequent host source of P. argentipes bloodmeals. The purpose of this study was to determine the efficacy of a single oral dose fipronil against adult and larval P. argentipes. Ten Bos indicus cattle were used during the study in a controlled environment. The study was conducted in Bihar, India, and involved adult and larval bioassays using laboratory-reared P. argentipes. The results were positive in that they led to up to 100% mortality in both adult and larval sand flies over a 21-d period after a single dose of fipronil.
内脏利什曼病（VL）是一种流行于印度次大陆的虫媒疾病。在旧世界，白蛉属的沙蝇是 VL 的传播媒介，而在印度次大陆，传播媒介是白蛉属的银足白蛉。牛在该地区是一种商品，也是银足白蛉经常吸食血液的宿主。本研究的目的是确定单口服剂量氟虫腈对成年和幼虫期银足白蛉的功效。在这项研究中，使用了 10 头印度野牛，在受控环境下进行。该研究在印度比哈尔邦进行，涉及使用实验室饲养的银足白蛉进行成虫和幼虫生物测定。结果是积极的，在单次氟虫腈剂量后 21 天内，成虫和幼虫沙蝇的死亡率高达 100%。
