Anikin V V, Zakharov I Iu
Ter Arkh. 1990;62(4):43-5.
As many as 71 men fit for work (aged 32.6 years on the average) suffering from stage II alcoholism were examined with the aid of variation pulsimetry. The findings obtained were compared with the data of electrophysiological exploration of the heart by transesophageal pacing. In the majority of the patients (80.2% of cases), the changes in vegetative homeostasis manifested themselves primarily by activation of the sympathetic nervous system and combined both with a noticeable decrease of sinus node automatism function and an appreciable deterioration of conduction in the sinoatrial zone and atrioventricular junction. In addition, sinus node automatism function and sinoatrial conduction were inhibited to a greater degree in sympatheticotonia whereas deterioration of antegrade impulse conduction in the atrioventricular junction manifested itself mostly in association with predominant vagus influences. It is emphasized that in patients with alcoholism, sympatheticotonia was attended by different impairments of the heart rhythm in half of the cases.
对多达71名适合工作的II期酒精中毒男性患者（平均年龄32.6岁）借助变时性脉搏测量法进行了检查。将所得结果与经食管起搏对心脏进行电生理探查的数据进行了比较。在大多数患者中（80.2%的病例），自主神经稳态的变化主要表现为交感神经系统的激活，同时伴有窦房结自律功能明显下降以及窦房区和房室交界区传导明显恶化。此外，在交感神经张力亢进时，窦房结自律功能和窦房传导受到的抑制程度更大，而房室交界区顺行冲动传导的恶化大多表现为主要受迷走神经影响。需要强调的是，在酒精中毒患者中，一半的病例交感神经张力亢进伴有不同程度的心律失常。
