• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

甲氨蝶呤治疗后发生大出血的宫颈妊娠。

Cervical pregnancy with massive bleeding after treatment with methotrexate.

作者信息

Saeng-anan Ubol, Sreshthaputra Opas, Sukpan Kornkanok, Tongsong Theera

机构信息

Department of Obstetrics and Gynecology, Chiang Mai University, Chiang Mai, Thailand.

出版信息

BMJ Case Rep. 2013 Aug 8;2013:bcr2013200440. doi: 10.1136/bcr-2013-200440.

DOI:10.1136/bcr-2013-200440
PMID:23929636
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3762407/
Abstract

This report describes a catastrophic bleeding following methotrexate treatment of cervical pregnancy and dramatic response to Bakri surgical obstetric silicone (SOS) balloon tamponade in controlling massive bleeding. A 42-year-old woman was diagnosed for cervical pregnancy with a viable fetus at 12 weeks by transvaginal ultrasound. Conservative treatment with intrafetal potassium chloride injection and systemic methotrexate were instituted. On the sixth day of therapy, catastrophic bleeding lead to hypovolemic shock. After resuscitation and blood transfusion, we attempt to control the bleeding with evacuation and curettage but was unsuccessful. Bakri SOS balloon tamponade was applied with immediate and effective response. Nevertheless, total abdominal hysterectomy was performed. In conclusion, conservative treatment of cervical pregnancy with systemic methotrexate could be catastrophic in some patients. Control of active bleeding with Bakri SOS balloon tamponade may possibly be helpful in case of uncontrolled bleeding in selected cases.

摘要

本报告描述了甲氨蝶呤治疗宫颈妊娠后发生的灾难性出血,以及Bakri产科手术硅胶(SOS)球囊填塞术在控制大出血方面的显著效果。一名42岁女性经阴道超声诊断为宫颈妊娠,孕12周,胎儿存活。采用胎儿内氯化钾注射和全身甲氨蝶呤进行保守治疗。治疗第6天,灾难性出血导致低血容量性休克。复苏和输血后,我们试图通过刮宫术控制出血,但未成功。应用Bakri SOS球囊填塞术,立即取得了有效反应。尽管如此,仍进行了全腹子宫切除术。总之,对某些患者而言,全身应用甲氨蝶呤保守治疗宫颈妊娠可能会带来灾难性后果。在特定病例中,若出血无法控制,使用Bakri SOS球囊填塞术控制活动性出血可能会有所帮助。

相似文献

1
Cervical pregnancy with massive bleeding after treatment with methotrexate.甲氨蝶呤治疗后发生大出血的宫颈妊娠。
BMJ Case Rep. 2013 Aug 8;2013:bcr2013200440. doi: 10.1136/bcr-2013-200440.
2
Acute hemorrhage related to a residual cervical pregnancy: management with curettage, tamponade, and cerclage.与残留宫颈妊娠相关的急性出血:刮宫、填塞和环扎术治疗。
J Minim Invasive Gynecol. 2013 Nov-Dec;20(6):907-11. doi: 10.1016/j.jmig.2013.05.011. Epub 2013 Jul 20.
3
Successful management of a cervical twin pregnancy: neoadjuvant systemic methotrexate and prophylactic high cervical cerclage before curettage.宫颈双胎妊娠的成功管理:刮宫术前新辅助全身甲氨蝶呤治疗及预防性高位宫颈环扎术
Fertil Steril. 2009 Mar;91(3):935.e17-9. doi: 10.1016/j.fertnstert.2008.11.009. Epub 2008 Dec 24.
4
Conservative medical management of advanced cervical ectopic pregnancies.晚期宫颈异位妊娠的保守药物治疗
Obstet Gynecol Surv. 2000 Jun;55(6):385-9. doi: 10.1097/00006254-200006000-00024.
5
Viable cervical pregnancy managed with systemic Methotrexate, uterine artery embolization, and local tamponade with inflated Foley catheter balloon.
Am J Perinatol. 2003 Jul;20(5):263-7. doi: 10.1055/s-2003-42341.
6
Successful conservative treatment of a cervical ectopic pregnancy at 13 weeks.13周宫颈异位妊娠的成功保守治疗
Clin Exp Obstet Gynecol. 2016;43(2):291-3.
7
Emergency surgical procedure for failed methotrexate treatment of cervical pregnancy: a case report.甲氨蝶呤治疗宫颈妊娠失败后的急诊手术治疗:一例病例报告
Eur J Contracept Reprod Health Care. 2007 Dec;12(4):391-5. doi: 10.1080/13625180701502351.
8
Methotrexate for cervical pregnancy. A case report.甲氨蝶呤治疗宫颈妊娠。一例病例报告。
J Reprod Med. 2003 Feb;48(2):130-2.
9
Evacuation of the cervix after methotrexate administration in the treatment of cervical pregnancy: five cases.甲氨蝶呤治疗宫颈妊娠后宫颈排空:5例报告
Reprod Biomed Online. 2006 Apr;12(4):487-92. doi: 10.1016/s1472-6483(10)62003-2.
10
Cervical ectopic pregnancy. Diagnosis with endovaginal ultrasound examination and successful treatment with methotrexate.宫颈异位妊娠。经阴道超声检查诊断并成功应用甲氨蝶呤治疗。
Arch Fam Med. 2000 Jan;9(1):72-7. doi: 10.1001/archfami.9.1.72.

引用本文的文献

1
A Systematic Review about Cervical Pregnancy and our Experience.关于宫颈妊娠的系统评价及我们的经验
Acta Med Litu. 2024;31(1):92-101. doi: 10.15388/Amed.2024.31.1.13. Epub 2024 Feb 27.
2
Double Balloon Cervical Ripening Catheter for Control of Massive Hemorrhage in a Cervical Ectopic Pregnancy.双球囊宫颈成熟导管用于控制宫颈异位妊娠中的大量出血
Case Rep Obstet Gynecol. 2017;2017:9396075. doi: 10.1155/2017/9396075. Epub 2017 Feb 2.
3
Conservative management of cervical pregnancy with intramuscular administration of methotrexate and KCl injection: Case report and review of the literature.甲氨蝶呤肌肉注射联合氯化钾注射保守治疗宫颈妊娠:病例报告及文献复习
World J Clin Cases. 2015 Jan 16;3(1):81-4. doi: 10.12998/wjcc.v3.i1.81.

本文引用的文献

1
Multidose methotrexate treatment of cervical pregnancy.多剂量甲氨蝶呤治疗宫颈妊娠
J Obstet Gynaecol Can. 2012 Apr;34(4):359-362. doi: 10.1016/S1701-2163(16)35217-3.
2
[Cervical pregnancy can be managed conservatively with methotrexate].宫颈妊娠可用甲氨蝶呤进行保守治疗。
Ugeskr Laeger. 2011 Oct 24;173(43):2722-3.
3
[Treatment of cervical pregnancy with systemic methotrexate and KCI solution injection into the gestational sac--case report and review of literature].[全身应用甲氨蝶呤联合氯化钾溶液注入妊娠囊治疗宫颈妊娠——病例报告及文献复习]
Ginekol Pol. 2011 May;82(5):386-9.
4
Fertility preservation in heterotopic cervical pregnancy: what is the best procedure?异位宫颈妊娠的生育力保存:哪种方法最佳?
Fetal Diagn Ther. 2011;30(3):229-33. doi: 10.1159/000329307. Epub 2011 Aug 3.
5
Cervical pregnancy.宫颈妊娠。
Fertil Steril. 2011 May;95(6):2123.e3-4. doi: 10.1016/j.fertnstert.2011.01.016. Epub 2011 Feb 3.
6
An efficient conservative treatment modality for cervical pregnancy: angiographic uterine artery embolization followed by immediate curettage.一种有效的宫颈妊娠保守治疗方法:血管造影子宫动脉栓塞后立即刮宫。
Am J Obstet Gynecol. 2011 Jan;204(1):31.e1-7. doi: 10.1016/j.ajog.2010.08.048.
7
Modification of conservative treatment of heterotopic cervical pregnancy by Foley catheter balloon fixation with cerclage sutures at the level of the external cervical os: a case report.采用福来导尿管球囊固定并在宫颈外口水平进行环扎缝合改良保守治疗宫颈异位妊娠:一例报告
J Med Case Rep. 2010 Jul 16;4:212. doi: 10.1186/1752-1947-4-212.
8
Conservative management of cervical pregnancy. A case-report.宫颈妊娠的保守治疗。病例报告。
Tunis Med. 2008 Sep;86(9):827-9.
9
Conservative management of spontaneous heterotopic cervical pregnancy using an aspiration cannula and pediatric Foley catheter.使用抽吸套管和小儿Foley导管对自发性宫颈异位妊娠进行保守治疗。
Ultrasound Obstet Gynecol. 2009 Jun;33(6):733-4. doi: 10.1002/uog.6363.
10
Cervical pregnancy treated with systemic methotrexate administration and resectoscopy.采用全身应用甲氨蝶呤及宫腔镜切除术治疗宫颈妊娠。
Taiwan J Obstet Gynecol. 2008 Dec;47(4):443-7. doi: 10.1016/S1028-4559(09)60015-2.