University of Alabama at Birmingham.
Blood. 2013 Aug 8;122(6):857-8. doi: 10.1182/blood-2013-06-506584.
In this issue of Blood, Gertner-Dardenne et al show that B- and T-lymphocyte attenuator (BTLA) functions as an inhibitory receptor on gd T cells and suggest that disruption of this inhibitory pathway in tumor-reactive gd T cells may result in enhanced antitumor responses.
在本期《Blood》中,Gertner-Dardenne 等人表明 B 和 T 淋巴细胞衰减器(BTLA)在 gd T 细胞上作为抑制性受体发挥作用,并提示肿瘤反应性 gd T 细胞中这种抑制途径的破坏可能导致增强的抗肿瘤反应。