Department of Biomedical Engineering, School of Life Science, Beijing Institute of Technology, Beijing 100081, China.
Comput Biol Med. 2013 Sep;43(9):1221-33. doi: 10.1016/j.compbiomed.2013.06.003. Epub 2013 Jun 18.
In single photon emission computed tomography (SPECT), due to the attenuation of gamma photons, the analytical reconstruction is complicated, where attenuation should be compensated to obtain quantitative results. We know that the resolution of SPECT is low. The cone-beam SPECT reconstruction can improve the photon density and spatial resolution of the reconstructed image. In practice, to minimize the effect of distance-dependent resolution variation (DDRV), the detector should be set as close as possible to the patient. Therefore it would be more efficacious for the orbit of the detector to be elliptical or another shape. In this paper, based on the Novikov's reconstruction formula and our Ray-driven Technology, we present an analytical cone-beam SPECT reconstruction algorithm for general non-circular orbit. The simulation results demonstrate the accuracy and robustness of our method.
在单光子发射计算机断层扫描（SPECT）中，由于伽马光子的衰减，分析重建变得复杂，需要对衰减进行补偿以获得定量结果。我们知道 SPECT 的分辨率较低。锥束 SPECT 重建可以提高重建图像的光子密度和空间分辨率。在实践中，为了最小化距离相关分辨率变化（DDRV）的影响，探测器应尽可能靠近患者。因此，探测器的轨道为椭圆形或其他形状会更有效。在本文中，我们基于 Novikov 的重建公式和我们的射线驱动技术，提出了一种针对一般非圆形轨道的分析锥束 SPECT 重建算法。模拟结果证明了我们方法的准确性和鲁棒性。
