Department of Cardiology, LAC-USC Medical Center, Keck School of Medicine, Los Angeles, CA 91011, USA.
Cardiol Clin. 2013 Aug;31(3):417-30. doi: 10.1016/j.ccl.2013.05.006.
Patent ductus arteriosus in adults is usually an isolated lesion with a small to moderate degree of shunt, as a larger shunt becomes symptomatic earlier in childhood. The classic murmur of patent ductus arteriosus may be the first clue to its presence, or it may be detected accidently by transthoracic echocardiography, computed tomography, or magnetic resonance angiography for an unrelated condition. The percutaneous approach is safe and effective in more than 98% of patients. Subacute bacterial endocarditis prophylaxis is not indicated routinely except for 6 months following the closure percutaneously or surgically.
成人动脉导管未闭通常是一种孤立的病变,伴有小至中度分流,因为较大的分流在儿童期早期就会出现症状。动脉导管未闭的典型杂音可能是其存在的第一个线索,也可能是在经胸超声心动图、计算机断层扫描或磁共振血管造影检查无关疾病时意外发现。经皮方法在超过 98%的患者中是安全有效的。除经皮或手术关闭后 6 个月外,通常不常规预防性使用抗生素治疗亚急性细菌性心内膜炎。