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[用“适度”剂量肝素治疗下肢远端静脉血栓形成]

[Treatment of distal venous thrombosis of the lower extremity with "moderated" doses of heparin].

作者信息

Rosell Pradas J, Ruiz Morales M, Tovar Martínez J L, Vara Thorbeck R

机构信息

Cátedra de Patología y Clínica Quirúrgica, Hospital Universitario, Granada, España.

出版信息

Angiologia. 1990 May-Jun;42(3):100-4.

PMID:2393158
Abstract

The effectiveness of a therapeutic protocol, using 15,000 to 22,500 IU/day of heparin by subcutaneous injection, to treat the distal postoperative vein thrombosis on the lower limb, was evaluated. The study was made on 427 patients, which were analyzed by the Fibrinogen I125 marked accumulation test, to give an early diagnostic and follow-up of their thrombosis (thrombus lysis, stabilization or expansion). Treatment made, showed its efficacy preventing from proximal expansion, as well as avoiding pulmonary embolism and postphlebitic syndrome. Its cost is lower than other therapeutic option's costs, and it doesn't extend the hospital stay.

摘要

评估了一种治疗方案的有效性,该方案为每天皮下注射15,000至22,500国际单位肝素,用于治疗下肢远端术后静脉血栓形成。对427名患者进行了研究,通过纤维蛋白原I125标记积聚试验对其进行分析,以便对他们的血栓形成(血栓溶解、稳定或扩展)进行早期诊断和随访。所进行的治疗显示出其在预防近端扩展、避免肺栓塞和静脉炎后综合征方面的疗效。其成本低于其他治疗选择的成本,并且不会延长住院时间。

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Angiologia. 1990 May-Jun;42(3):100-4.
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